An optogenetic toolkit for robust activation of FGF, BMP, & Nodal signaling in zebrafish.

Iannucci LE, Maria Thomas VS, Anderson WK, Murphy MR, Donahue CET, Campbell CE, Monaghan MT, Saul AJ, Rogers KW
Dev Biol. 2026 Aug;536:155-171. doi: 10.1016/j.ydbio.2026.05.003. Epub 2026 May 18. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
232639	pCS2-Opto-zFGFR1a	Zebrafish FGFR1a receptor kinase domain fused to VfLOV
232640	pCS2-Opto-Acvr1ba-P2A-Acvr2ba	Optogenetic Nodal activators from Sako et al. 2016 (Cell Reports) separated by a P2A peptide for singe-transcript expression