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Structure and engineering of the large serine recombinase Bxb1 for gene integration.

Soma T, Hiraizumi M, Fell CW, Tagliaferri D, Lequyer J, Okazaki S, Isayama Y, Kato K, Sapkota S, Ramani H, Arya B, Schmitt-Ulms C, Yamashita K, Gootenberg JS, Abudayyeh OO, Nishimasu H
Mol Cell. 2026 Jun 18;86(12):2247-2262.e7. doi: 10.1016/j.molcel.2026.05.018. Epub 2026 Jun 8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
260029pDY2365 pCMV-PE2-Bxb1_v12k_q226k_h334k (enPASTE)PASTE v1 plasmid with activity enhancement
260030pDY2279 pCAG-Bxb1_v12k_q226k_h334k (enBxb1)Bxb1 plasmid with enhanced activity

Antibodies from Article