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UBQLN2 restrains the domesticated retrotransposon PEG10 to maintain neuronal health in ALS.

Black HH, Hanson JL, Roberts JE, Leslie SN, Campodonico W, Ebmeier CC, Holling GA, Tay JW, Matthews AM, Ung E, Lau CI, Whiteley AM
Elife. 2023 Mar 23;12:e79452. doi: 10.7554/eLife.79452. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
260088Hs PEG10-Dendra2 gag-polExpression of Human PEG10-dendra2 and CFP using IRES
260090Mm HA-Peg10 (D420A)Expression of Mouse proteolytically inactive 2x HA-tagged PEG10
260092Hs HA-PEG10 Gag-polExpression of Human 2x HA-tagged PEG10
260093Hs HA-PEG10 Gag-pol (D370A)Expression of Human proteolytically inactive 2x HA-tagged PEG10
260095Hs HA-PEG10 Gag Expression of Human 2x HA-tagged PEG10 Gag
260099Hs HA-PEG10 gag-pol isoform3Expression of Human 2x HA-tagged PEG10 isoform3
260100Hs PEG10-Dendra2 gag-pol isoform3Expression of Human PEG10-dendra2 isoform3 and CFP using IRES
260102Hs PEG10-Dendra2 gagExpression of Human PEG10-dendra2 and CFP using IRES

Antibodies from Article