An activating calcium-sensing receptor variant with biased signaling reveals a critical residue for Galpha11 coupling.
Benson MR, Wyatt RA, Levine MA, Gorvin CM
J Bone Miner Res. 2025 Feb 2;40(2):270-282. doi: 10.1093/jbmr/zjae199.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 261429 | pCMV-Flag-SNAP-CaSR | Express CaSR (calcium sensing receptor) with Flag and SNAP tags under the control of the CMV promoter |
| 261430 | pCMV-Flag-SNAP-CaSR-L723R | Express L723R (Leu723Arg) CaSR gain-of-function variant under the control of the CMV promoter |