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Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor.

Onabajo OO, Banday AR, Stanifer ML, Yan W, Obajemu A, Santer DM, Florez-Vargas O, Piontkivska H, Vargas JM, Ring TJ, Kee C, Doldan P, Tyrrell DL, Mendoza JL, Boulant S, Prokunina-Olsson L
Nat Genet. 2020 Dec;52(12):1283-1293. doi: 10.1038/s41588-020-00731-9. Epub 2020 Oct 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
263184dACE2-Myc-DDKExpress dACE2-Myc-FLAG on mammalian cells
263185dACE2-GFPExpress dACE2-TurboGFP on mammalian cells

Antibodies from Article