iSCORE-PD: an isogenic stem cell collection to research Parkinson's disease.
Busquets O, Li H, Syed KM, Jerez PA, Dunnack J, Lo Bu R, Verma Y, Pangilinan GR, Martin A, Straub J, Du Y, Simon VM, Poser S, Bush Z, Diaz J, Sahagun A, Gao J, Hong S, Hernandez DG, Levine KS, Pochet N, Booth EO, Blanchette M, Bateup HS, Rio DC, Blauwendraat C, Hockemeyer D, Soldner F
Nat Commun. 2026 Jun 17;17(1):7682. doi: 10.1038/s41467-026-74355-8.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 214929 | Px330-EGFP-DJ1 X1-5DEL gRNA (1)-CRISPR_Cas9 | 5' gRNA to target Exon 1-5 of DJ-1/PARK7 (dual guide CRISPR) |
| 214930 | Px330-mCherry-DJ1 X1-5DEL sgRNA (2)-CRISPR_Cas9 | 3' gRNA to target Exon 1-5 of DJ-1/PARK7 (dual guide CRISPR) |
| 214931 | Px330-mCherry-DJ1 X1-5DEL sgRNA (3)-CRISPR_Cas9 | 3' gRNA to target Exon 1-5 of DJ-1/PARK7 (dual guide CRISPR) - Secondary targeting for homozygosity |