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The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha.
Hu CJ, Sataur A, Wang L, Chen H, Simon MC
Mol Biol Cell. 2007 Nov;18(11):4528-42. Epub 2007 Sep 5.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
44027pcDNA3 mHIF-2α MYC (P405A/P530V/N851A)
44028pcDNA3 mHIF-1α MYC (P402A/P577A/N813A)