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TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation.
Blonska M, Shambharkar PB, Kobayashi M, Zhang D, Sakurai H, Su B, Lin X J Biol Chem. 2005 Dec 30;280(52):43056-63. Epub 2005 Oct 31.