Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation.
Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL
Mol Cell. 2000 Dec . 6(6):1365-75. PubMed Article
Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL
Mol Cell. 2000 Dec . 6(6):1365-75. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 11746 | pCMV5B-Flag-Smurf2 wt | |
| 11747 | pCMV5B-Flag-Smurf2 C716A | |
| 13504 | pGEX4T1-Smurf2 wt | |
| 13505 | pGEX4T1-Smurf2 C716A |