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Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation.
Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL
Mol Cell. 2000 Dec . 6(6):1365-75.
PubMed Journal

Plasmids from Article

ID Plasmid  
11746 pCMV5B-Flag-Smurf2 wt Add to Cart
11747 pCMV5B-Flag-Smurf2 C716A Add to Cart
13504 pGEX4T1-Smurf2 wt Add to Cart
13505 pGEX4T1-Smurf2 C716A Add to Cart

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