GSK3beta phosphorylation of the KLF6 tumor suppressor promotes its transactivation of p21.
Lang UE, Kocabayoglu P, Cheng GZ, Ghiassi-Nejad Z, Munoz U, Vetter D, Eckstein DA, Hannivoort RA, Walsh MJ, Friedman SL
Oncogene. 2012 Oct 22. doi: 10.1038/onc.2012.457. PubMed Article
Lang UE, Kocabayoglu P, Cheng GZ, Ghiassi-Nejad Z, Munoz U, Vetter D, Eckstein DA, Hannivoort RA, Walsh MJ, Friedman SL
Oncogene. 2012 Oct 22. doi: 10.1038/onc.2012.457. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 49488 | flag-hKLF6 (1006) | expresses human flag tagged KLF6 in mammalian cells |
| 49489 | flag-hKLF6-4A (1010) | expresses human Flag tagged KLF6 with 4A mutation |
| 49490 | Flag-KLF6-4D (1054) | expresses human Flag tagged KLF6 with 4D mutation |
| 49491 | GSK3beta (1015) | expresses human Gsk3beta |
| 49492 | GSK3betaS9A (1016) | expresses human Gsk3beta with S9A (constitutively active) mutation |
| 49496 | flag-hKLF6 P149S (1008) | expresses human Flag tagged KLF6 with P149S mutation |
| 49497 | hKLF6 P148L (1009) | expresses human KLF6 with P148L mutation |