The clustering of GABA(A) receptor subtypes at inhibitory synapses is facilitated via the direct binding of receptor alpha 2 subunits to gephyrin.
Tretter V, Jacob TC, Mukherjee J, Fritschy JM, Pangalos MN, Moss SJ
J Neurosci. 2008 Feb 6;28(6):1356-65. doi: 10.1523/JNEUROSCI.5050-07.2008.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 49168 | GABA(A) receptor subunit a1SE | pHluorin-tagged GABA A receptor subunit (alpha 1) produces minimal fluorescence during trafficking and a robust fluorescent signal at the cell surface |
| 49169 | GABA(A) receptor subunit a2SE | pHluorin-tagged GABA A receptor subunit (alpha 2) produces minimal fluorescence during trafficking and a robust fluorescent signal at the cell surface |