The clustering of GABA(A) receptor subtypes at inhibitory synapses is facilitated via the direct binding of receptor alpha 2 subunits to gephyrin.
Tretter V, Jacob TC, Mukherjee J, Fritschy JM, Pangalos MN, Moss SJ
J Neurosci. 2008 Feb 6;28(6):1356-65. doi: 10.1523/JNEUROSCI.5050-07.2008. PubMed Article
Tretter V, Jacob TC, Mukherjee J, Fritschy JM, Pangalos MN, Moss SJ
J Neurosci. 2008 Feb 6;28(6):1356-65. doi: 10.1523/JNEUROSCI.5050-07.2008. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
49168 | GABA(A) receptor subunit a1SE | pHluorin-tagged GABA A receptor subunit (alpha 1) produces minimal fluorescence during trafficking and a robust fluorescent signal at the cell surface |
49169 | GABA(A) receptor subunit a2SE | pHluorin-tagged GABA A receptor subunit (alpha 2) produces minimal fluorescence during trafficking and a robust fluorescent signal at the cell surface |