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Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop.
Oliver TG, Meylan E, Chang GP, Xue W, Burke JR, Humpton TJ, Hubbard D, Bhutkar A, Jacks T
Mol Cell. 2011 Jul 8;43(1):57-71. doi: 10.1016/j.molcel.2011.06.012.
PubMed Journal

Plasmids from Article

ID Plasmid  
52057 pCMV-myc3-Mdm2 D367E Add to Cart
52058 pCMV-myc3-Mdm2 D367A Add to Cart
52059 pCMV-myc3-Mdm2 p60 Add to Cart
52061 MSCV-shCasp2-IRES-GFP Add to Cart