A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction.
Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC
Cell. 2014 Feb 13;156(4):705-16. doi: 10.1016/j.cell.2014.01.019. PubMed Article
Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC
Cell. 2014 Feb 13;156(4):705-16. doi: 10.1016/j.cell.2014.01.019. PubMed Article
Plasmids from Article
ID | Plasmid | Purpose | |
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52736 | PLC-TIR-GFP | Retroviral vector expresses the lipid binding domain of PLCd1 fused to the TIR of hTIRAP and GFP. Also contains IRES-hCD2 as selectable marker |
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52737 | PX-TIR-GFP | Retroviral vector expresses the lipid binding domain of p40-phox fused to the TIR of hTIRAP and GFP. Also contains IRES-hCD2 as selectable marker |
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52738 | SLP2a-TIR-GFP | Retroviral vector expresses the lipid binding domain of SLP2a fused to the TIR of hTIRAP and GFP. Also contains IRES-hCD2 as selectable marker |
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52739 | TIRAP-GFP | Retroviral vector expresses WT hTIRAPfused to GFP. Also contains IRES-hCD2 as selectable marker |
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52740 | TIRAP-TAP_IRES_GFP | Retroviral vector expresses hTIRAP-3xHA and a target site for the biotin ligase BirA upstream of IRES and GFP |
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