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Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2.
Bamming D, Horvath CM
J Biol Chem. 2009 Apr 10;284(15):9700-12. doi: 10.1074/jbc.M807365200. Epub 2009 Feb 11. PubMed Article

Plasmids from Article

ID Plasmid Purpose
52875pEF-Bos-FLAG MDA5 MIExpresses MDA5 with a mutation to motif I in mammalian cells
52876pEF-Bos-FLAG MDA5 MIIIExpresses MDA5 with a mutation to motif III in mammalian cells
52877pEF-Bos-FLAG RIG-I MIIIExpresses RIG-I with a mutation to motif III in mammalian cells
58681CMV-10-3xFLAG-LGP2Expresses 3x Flag-tagged LGP2 in mammalian cells
58682CMV-10-3xFLAG-LGP2-MIExpresses LGP2 with a mutation to motif I in mammalian cells
58683CMV-10-3xFLAG-LGP2-MIIIExpresses LGP2 with a mutation to motif III in mammalian cells

Antibodies from Article