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Mouse models of human AML accurately predict chemotherapy response.
Zuber J, Radtke I, Pardee TS, Zhao Z, Rappaport AR, Luo W, McCurrach ME, Yang MM, Dolan ME, Kogan SC, Downing JR, Lowe SW
Genes Dev. 2009 Apr 1;23(7):877-89. doi: 10.1101/gad.1771409.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
60832MSCV-AML1/ETO-IRES-GFPAML1/ETO9a cDNA was generated by PCR from full-length human AML1/ETO-IRES-GFP and subcloned into MSCV-IRES-GFP
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60834MSCV-Luciferase-IRES-NrasG12DMouse NrasG12D was amplified and mutated by PCR from IMAGE clone 6475312 (Invitrogen) and cloned downstream from the IRES; subsequently Luciferase was cloned upstream of the IRES
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