An extranuclear locus of cAMP-dependent protein kinase action is necessary and sufficient for promotion of spiral ganglion neuronal survival by cAMP.
Bok J, Zha XM, Cho YS, Green SH
J Neurosci. 2003 Feb 1;23(3):777-87. PubMed
Bok J, Zha XM, Cho YS, Green SH
J Neurosci. 2003 Feb 1;23(3):777-87. PubMed
Plasmids from Article
ID | Plasmid | Purpose | |
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61091 | GPKA | GFP-tagged cAMP-dependent PKA catalytic subunit |
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61092 | GPKAnes | GFP-tagged PKA catalytic subunit targeted to the extranuclear cytoplasm by addition of a nuclear export signal |
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61094 | GPKAnls | GFP-tagged PKA catalytic subunit targeted to the nucleus by addition of a nuclear localization signal |
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