Michael J. Fox Foundation Plasmid Resource
Addgene is working with The Michael J. Fox Foundation (MJFF) along with individual laboratories to assemble a Parkinson's disease plasmid resource for the scientific research community.
MJFF has created a number of plasmids for expression of LRRK2 protein domain variants. Browse the full list below.
| ID | Plasmid | Gene/Insert | Vector Type | Mutations |
|---|---|---|---|---|
| 38005 | pET-21a(+)/MBP-His-PINK1 | PINK1 (Homo sapiens) | Bacterial Expression | |
| 38006 | pET-21a(+)/MBP-His | MBP (Maltose binding protein) (Synthetic) | Bacterial Expression | |
| 38008 | pFastBac1/MBP-His | MBP (Maltose binding protein) (Synthetic) | Insect Expression ; Baculovirus expression | |
| 39529 | pENTR221 LRRK2 wt | LRRK2 (Homo sapiens) | Gateway compatible cloning vector | |
| 40364 | pBACgus4x/cdc37/LRRK2 1867-2186 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40365 | pBACgus4x/cdc37/LRRK2 1867-2186_G2019S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40366 | pBACgus4x/cdc37/LRRK2 1867-2186_C2024S/C2025S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40367 | pBACgus4x/cdc37/LRRK2 1867-2186_T2031E | LRRK2 (Homo sapiens) | Baculovirus | |
| 40368 | pBACgus4x/cdc37/LRRK2 1867-2141 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40369 | pBACgus4x/cdc37/LRRK2 1867-2161 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40370 | pBACgus4x/cdc37/LRRK2 1867-2176 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40371 | pBACgus4x/cdc37/LRRK2 1867-2161_G2019S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40372 | pBACgus4x/cdc37/LRRK2 1867-2161_C2024S/C2025S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40373 | pBACgus4x/cdc37/LRRK2 1867-2161_T2031E | LRRK2 (Homo sapiens) | Baculovirus | |
| 40374 | pBACgus/LRRK2 1867-2186 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40375 | pBACgus/LRRK2 C-His | LRRK2 (Homo sapiens) | Baculovirus | |
| 40376 | pBACgus/LRRK2 1867-2141 C-His | LRRK2 (Homo sapiens) | Baculovirus | |
| 40377 | pBACgus/LRRK2 1867-2161 C-His | LRRK2 (Homo sapiens) | Baculovirus | |
| 40378 | pBACgus/LRRK2 1867-2176 C-His | LRRK2 (Homo sapiens) | Baculovirus | |
| 40379 | pBACgus/LRRK2 C-His_T2031E | LRRK2 (Homo sapiens) | Baculovirus | |
| 40380 | pBACgus/LRRK2 1867-2161 C-His_T2031E | LRRK2 (Homo sapiens) | Baculovirus | |
| 40381 | pBACgus/LRRK2 C-His_G2019S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40382 | pBACgus/LRRK2 1867-2161 C-His_G2019S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40383 | pBACgus/LRRK2 C-His_C2024S/C2025S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40384 | pBACgus/LRRK2 1867-2161 C-His_C2024S/C2025S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40385 | pBACgus4x/Parkin | Parkin (Homo sapiens) | Baculovirus | |
| 40386 | pBACgus_Sumostar/LRRK2 1867-2186 | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40387 | pBACgus_Sumostar/LRRK2 1867-2186_G2019S | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40388 | pBACgus_Sumostar/LRRK2 1867-2186_C2024S/C2025S | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40389 | pBACgus_Sumostar/LRRK2 1867-2186_T2031E | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40390 | pBACgus_Sumostar/LRRK2 1867-2141 | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40391 | pBACgus_Sumostar/LRRK2 1867-2161 | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40392 | pBACgus_Sumostar/LRRK2 1867-2176 | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40393 | pBACgus_Sumostar/LRRK2 1867-2161_G2019S | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40394 | pBACgus_Sumostar/LRRK2 1867-2161_C2024S/C2025S | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40395 | pBACgus_Sumostar/LRRK2 1867-2161_T2031E | SUMO (Synthetic), LRRK2 (Homo sapiens) | Baculovirus | |
| 40396 | pBACgus4x/cdc37/RocCOR LRRK2 1867-2141 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40397 | pBACgus4x/cdc37/RocCOR LRRK2 1867-2161 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40398 | pBACgus4x/cdc37/RocCOR LRRK2 1867-2176 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40399 | pBACgus N-His/GST | GST (Synthetic) | Baculovirus | |
| 40402 | pBACgus4x/Parkin/RocCOR LRRK2 1867-2176 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40403 | pBACgus N-His/GST/LRRK2 1867-2186 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40404 | pBACgus N-His/GST/LRRK2 1867-2141 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40405 | pBACgus N-His/GST/LRRK2 1867-2161 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40406 | pBACgus N-His/GST/LRRK2 1867-2176 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40407 | LRRK2_1867_2143 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40408 | LRRK2_1867_2136 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40409 | LRRK2_1867_2134 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40410 | LRRK2_1867_2170 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40411 | LRRK2_1867_2161_F1908Y | LRRK2 (Homo sapiens) | Baculovirus | |
| 40412 | LRRK2_1867_2161_V1922T_C2024S_C2025S_F2079Y_L2115A | LRRK2 (Homo sapiens) | Baculovirus | |
| 40413 | LRRK2_1867_2161_F1908A_L1936R_V2048S_F2079G | LRRK2 (Homo sapiens) | Baculovirus | |
| 40414 | LRRK2_1867_2161_F1908A_F2079G | LRRK2 (Homo sapiens) | Baculovirus | |
| 40415 | LRRK2_1867_2161_F1908A_V2048S_I2131Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40416 | LRRK2_1867_2161_I2131Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40417 | LRRK2_1867_2161_V2048S_F2079G | LRRK2 (Homo sapiens) | Baculovirus | |
| 40418 | LRRK2_1867_2161_F1908A_L1936R_V2048S_I2131Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40419 | LRRK2_1867_2161_V2048S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40420 | LRRK2_1867_2161_F1908A_L1936R_V2048S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40421 | LRRK2_1867_2161_F1908A_L1936R_I2131Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40422 | LRRK2_1867_2161_F1908A_L1936R_F2079G_I2131Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40423 | LRRK2_1867_2161_F1908A_L1936R_V2048S_F2079G_I2131Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40424 | LRRK2_1867_2161_L1914N_V2048T | LRRK2 (Homo sapiens) | Baculovirus | |
| 40425 | LRRK2_1867_2161_L1914N_V2048T_F2083Y_I2131S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40426 | LRRK2_1867_2161_L1914N_L1936Y_V2048T_F2083Y_I2131S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40427 | pEMB017 NP_9409803_LRRK2_1867_2161_L1914N_V2048T_F2083Y | LRRK2 (Homo sapiens) | Baculovirus | |
| 40428 | LRRK2_1867_2161_L1914A_L1976Y_C2024S_C2025S_I2049Q_F2083A | LRRK2 (Homo sapiens) | Baculovirus | |
| 40430 | LRRK2_1867_2161_L1914A_C2024S_C2025S_I2049Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40431 | LRRK2_1867_2161_L1914A_L1976Y | LRRK2 (Homo sapiens) | Baculovirus | |
| 40432 | LRRK2_1867_2161_L1916A_L1936R_L2005N_V2074Y_L2092Y | LRRK2 (Homo sapiens) | Baculovirus | |
| 40433 | LRRK2_1867_2161_L1914A_L1976Y_I2049Q_F2083A | LRRK2 (Homo sapiens) | Baculovirus | |
| 40434 | LRRK2_1867_2161_L1914A_L1976Y_I2049Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40435 | LRRK2_1867_2161_L1976Y_I2049Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40436 | LRRK2_1867_2161_L1914A | LRRK2 (Homo sapiens) | Baculovirus | |
| 40438 | LRRK2_1867_2161_L1916N_L1936R_L1976A_I2049A_L2092N | LRRK2 (Homo sapiens) | Baculovirus | |
| 40439 | LRRK2_1867_2161_L1916N_L1976A_I2049A_V2074A_L2092N | LRRK2 (Homo sapiens) | Baculovirus | |
| 40440 | LRRK2_1867_2161_V1922D_V2074A_L2115W | LRRK2 (Homo sapiens) | Baculovirus | |
| 40441 | LRRK2_1867_2161_V1922D_L2005R_V2074A_L2115W | LRRK2 (Homo sapiens) | Baculovirus | |
| 40442 | LRRK2_1867_2161_V1922D_L2005R_V2048S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40443 | LRRK2_1867_2161_V1922D_L2005R_V2074A | LRRK2 (Homo sapiens) | Baculovirus | |
| 40444 | LRRK2_1867_2161_V1922D_V2048S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40445 | LRRK2_1867_2161_F1908Y_L2115A | LRRK2 (Homo sapiens) | Baculovirus | |
| 40446 | LRRK2_1867_2161_F1908A_V2048S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40447 | LRRK2_1867_2161_F1908A_V2048S_F2079G_I2131Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40448 | LRRK2_1867_2161_I2131S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40449 | LRRK2_1867_2161_L1936Y_I2131S | LRRK2 (Homo sapiens) | Baculovirus | |
| 40451 | LRRK2_1867_2161_L1976Y_I2049Q_F2083A | LRRK2 (Homo sapiens) | Baculovirus | |
| 40452 | LRRK2_1867_2161_L1914A_L1976Y_C2024S_C2025S_I2049Q | LRRK2 (Homo sapiens) | Baculovirus | |
| 40499 | pEMB018 / LRRK2_BC_1300_2136 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40500 | pEMB018 / LRRK2_BC_1300_2148 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40501 | pEMB018 / LRRK2_BC_1300_2170 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40502 | pEMB018 / LRRK2_BC_1300_2210 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40503 | pEMB018 / LRRK2_BC_1309_2136 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40504 | pEMB018 / LRRK2_BC_1309_2170 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40505 | pEMB018 / LRRK2_BC_1309_2187 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40506 | pEMB018 / LRRK2_BC_1309_2210 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40507 | pEMB018 / LRRK2_BC_1320_2210 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40509 | pEMB018 / LRRK2_BC_1333_2148 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40510 | pEMB018 / LRRK2_BC_1333_2187 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40511 | pEMB018 / LRRK2_BC_1333_2210 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40512 | pEMB018 / LRRK2_BC_1500_2136 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40513 | pEMB018 / LRRK2_BC_1500_2148 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40514 | pEMB018 / LRRK2_BC_1500_2170 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40515 | pEMB018 / LRRK2_BC_1500_2187 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40516 | pEMB018 / LRRK2_BC_1500_2210 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40517 | pEMB018 / LRRK2_BC_1510_2170 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40518 | pEMB018 / LRRK2_BC_1510_2187 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40519 | pEMB018 / LRRK2_BC_1520_2148 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40520 | pEMB018 / LRRK2_BC_1520_2170 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40521 | pEMB018 / LRRK2_BC_1520_2187 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40522 | pEMB018 / LRRK2_BC_1520_2210 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40523 | pEMB018 / LRRK2_BC_1309_2527_M2397T | LRRK2 (Homo sapiens) | Baculovirus | |
| 40525 | pEMB018 / LRRK2_BC_1300_2232 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40526 | pEMB018 / LRRK2_BC_1309_2232 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40527 | pEMB018 / LRRK2_BC_1333_2232 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40528 | pEMB018 / LRRK2_BC_1300_2350 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40529 | pEMB018 / LRRK2_BC_1309_2350 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40530 | pEMB018 / LRRK2_BC_1500_2350 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40531 | pEMB018 / LRRK2_BC_1500_2232 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40532 | pEMB018 / LRRK2_BC_1847_2232 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40533 | pEMB018 / LRRK2_BC_1847_2350 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40535 | pEMB018 / LRRK2_BC_1882_2350 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40536 | pEMB018 / LRRK2_BC_1847_2527_M2397T | LRRK2 (Homo sapiens) | Baculovirus | |
| 40537 | pEMB018 / LRRK2_BC_1867_2527_M2397T | LRRK2 (Homo sapiens) | Baculovirus | |
| 40538 | pEMB018 / LRRK2_BC_1882_2527_M2397T | LRRK2 (Homo sapiens) | Baculovirus | |
| 40539 | pEMB018 / LRRK2_BC_1185_2136 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40540 | pEMB52/Bag5_1_447 | Bag5 (Homo sapiens) | Baculovirus | |
| 40541 | pEMB52/14-3-3_1_247 | YWHAG (Homo sapiens) | Baculovirus | |
| 40542 | pEMB52/Dvl1_1_670 | DVL1 (Homo sapiens) | Baculovirus | |
| 40543 | pEMB52/Armadillo_34_373 | LRRK2 | Baculovirus | |
| 40544 | pEMB52/Horse_34_374 | LRRK2 | Baculovirus | |
| 40545 | pEMB52/Turkey_34_374 | LRRK2 | Baculovirus | |
| 40549 | pEMB52 / Human_LRRK1_1_360 | LRRK1 (Homo sapiens) | Baculovirus | |
| 40550 | pEMB52 / Anemone_LRRK2_1_334 | LRRK2 | Baculovirus | |
| 40551 | pEMB52 / Urchin_LRRK2_1_335 | LRRK2 | Baculovirus | |
| 40552 | pEMB12/LRRK2_BC_1847_2170_P1865CCC | LRRK2 (Homo sapiens) | Baculovirus | |
| 40553 | pEMB12 / LRRK2_BC_1847_2210 | LRRK2 (Homo sapiens) | Baculovirus | |
| 40554 | pEMB44 / Lancelet_LRRK2_1_319 | LRRK2 | Baculovirus | |
| 40555 | pEMB44 / Mouse_LRRK2_1_342 | Lrrk2 (Mus musculus) | Baculovirus | |
| 40556 | pEMB44 / Zebrafish_LRRK2_1_338 | lrrk2 (Danio rerio) | Baculovirus | |
| 40557 | pEMB36(revcomp)/Dvl1_1_670 | DVL1 (Homo sapiens) | Baculovirus | |
| 40561 | pEMB403 Urchin_LRRK2_1_335 | LRRK2 | Baculovirus | |
| 40564 | pEMB12 LRRK2_BC_1847_2210_K1906M | LRRK2 (Homo sapiens) | Baculovirus | |
| 40565 | pEMB52 LRRK2_BC_1520_2210_I2211ENLYFQGWSHPQFEK | LRRK2 (Homo sapiens) | Baculovirus | |
| 40566 | pEMB52 LRRK2_BC_1520_2148_I2149ENLYFQGWSHPQFEK | LRRK2 (Homo sapiens) | Baculovirus | |
| 40567 | pEMB018 LRRK2_BC_1520_2148_K1906M | LRRK2 (Homo sapiens) | Baculovirus | |
| 51437 | human Alpha-synuclein | Alpha-synuclein (Homo sapiens) | Cloning | |
| 51486 | pET21a-alpha-synuclein | alpha-synuclein (Homo sapiens) | Bacterial Expression | |
| 51488 | pET3a-His-DJ1 | DJ1 (Homo sapiens) | Bacterial Expression | |
| 51489 | pET3a-DJ1 | DJ1 (Homo sapiens) | Bacterial Expression | |
| 89073 | pD434-SR mouse Alpha-synuclein | Alpha-synuclein (Mus musculus) | Bacterial Expression | |
| 89074 | pD454-SR rat Alpha-synuclein | Alpha-synuclein (Rattus norvegicus) | Bacterial Expression | |
| 89075 | pD454-SR mouse Alpha-synuclein | Alpha-synuclein (Mus musculus) | Bacterial Expression | |
| 89076 | pD434-SR rat Alpha-synuclein | Alpha-synuclein (Rattus norvegicus) | Bacterial Expression |