We narrowed to 8,835 results for: sgRNA

1. AAV-U6-sgPlxnb2-KO-1-EF1a-LibVec

   Plasmid

   #239597

   Purpose

   expresses guide#1 to knock-out mouse Plxnb2, via CRISPR-Cas9

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   Plxnb2 (Plxnb2 Mouse)
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. AAV-U6-sgPlxnb2-CRISPRa-3-EF1a-LibVec

   Plasmid

   #239596

   Purpose

   expresses guide#3 to boost the expression of mouse Plxnb2, via CRISPRa

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   Plxnb2 (Plxnb2 Mouse)
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. AAV-U6-sgPlxnb2-CRISPRa-1-EF1a-LibVec

   Plasmid

   #239594

   Purpose

   expresses guide#1 to boost the expression of mouse Plxnb2, via CRISPRa

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   Plxnb2 (Plxnb2 Mouse)
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. AAV-U6-sgPlxnb2-CRISPRa-2-EF1a-LibVec

   Plasmid

   #239595

   Purpose

   expresses guide#2 to boost the expression of mouse Plxnb2, via CRISPRa

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   Plxnb2 (Plxnb2 Mouse)
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pMCB320 sgCdkn1a.1

   Plasmid

   #227945

   Purpose

   sgRNA targeting Cdkn1a, mCherry, puromycin resistance, Mammalian expression, Mouse targeting, lentiviral, CRISPR

   Depositor

   Laura Attardi

   Article

   Boutelle et al Cell Death Differ. 2025 Apr 22. doi: 10.

   Insert

   Cdkn1a.1 (Cdkn1a Mouse)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   mouse U6

   Available Since

   April 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pMCB320 sgCdkn1a.2

   Plasmid

   #227946

   Purpose

   sgRNA targeting Cdkn1a, mCherry, puromycin resistance, Mammalian expression, Mouse targeting, lentiviral, CRISPR

   Depositor

   Laura Attardi

   Article

   Boutelle et al Cell Death Differ. 2025 Apr 22. doi: 10.

   Insert

   Cdkn1a.2 (Cdkn1a Mouse)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   mouse U6

   Available Since

   April 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pLV hU6-sgKRAS hUbC-dCas9-KRAB-T2a-GFP2

   Plasmid

   #184557

   Purpose

   Knockdown of murine KRAS gene by targeting the promoter region via CRISPRi system

   Depositor

   Sandeep Prabhu

   Article

   Qian et al Cell Rep. 2023 Jul 25;42(7):112794. doi:

   Insert

   Kirsten rat sarcoma virus (Kras Mouse)
   

   Use

   CRISPR, Lentiviral, and Mouse Targeting

   Tags

   Flag

   Expression

   Bacterial

   Available Since

   Oct. 15, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pENTR223-CMV-Cre-U6-sgKdm6a#4-U6-sgRb1-U6-sgTrp53-U6-sgRbl2

   Plasmid

   #209061

   Purpose

   Entry vector that endcodes sgRNAs against mouse Kdm6a, Rb1, Trp53, and Rbl2 and CMV Cre recombinase.

   Depositor

   Matthew Oser

   Article

   Duplaquet et al Nat Cell Biol. 2023 Sep;25(9):1346-1358.

   Insert

   KDM6A
   

   Use

   Gateway vector to be used for lr reaction

   Promoter

   U6

   Available Since

   Dec. 20, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pAd-PR.Cre

   Plasmid

   #192936

   Purpose

   Adenoviral expression vector encoding sgRNAs targeting Trp53 and Rb1 and Cre

   Depositor

   Thorsten Stiewe

   Article

   Merle et al Mol Cancer. 2022 Oct 3;21(1):191. doi: 1

   Inserts

   Trp53 (Trp53 Mouse)
   Rb1 (Rb1 Mouse)
   

   Use

   Adenoviral

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Dec. 12, 2022

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

10. pShuttle-PRL.Cre

    Plasmid

    #192934

    Purpose

    pShuttle.Cre encoding sgRNAs targeting Trp53, Rb1 and Rbl2 genes

    Depositor

    Thorsten Stiewe

    Article

    Merle et al Mol Cancer. 2022 Oct 3;21(1):191. doi: 1

    Insert

    Trp53, Rb1, Rbl2 (Trp53, Rb1 Mouse)
    

    Use

    Gateway-compatible vector

    Promoter

    U6

    Available Since

    Dec. 9, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

11. pAd-PR.CC9

    Plasmid

    #192935

    Purpose

    Adenoviral expression vector encoding sgRNAs targeting Trp53 and Rb1, Cre and Cas9

    Depositor

    Thorsten Stiewe

    Article

    Merle et al Mol Cancer. 2022 Oct 3;21(1):191. doi: 1

    Inserts

    Trp53 (Trp53 Mouse)
    Rb1 (Rb1 Mouse)
    

    Use

    Adenoviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    Dec. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pKHH030_sgAMBRA1#2

    Plasmid

    #174147

    Purpose

    Lentiviral vector expressing a sgRNA against the human AMBRA1 gene

    Depositor

    Julien Sage

    Article

    Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

    Insert

    AMBRA (AMBRA1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pKHH030_sgAMBRA1#1

    Plasmid

    #174146

    Purpose

    Lentiviral vector expressing a sgRNA against the human AMBRA1 gene

    Depositor

    Julien Sage

    Article

    Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

    Insert

    AMBRA (AMBRA1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pLEX307_CR-PDHA2S293A

    Plasmid

    #115204

    Purpose

    Lentiviral transduction and expression of CRISPR/Cas9-resistant PDHA2S293A into any mammalian cell (when using sgRNA 5'-ATGTAATGACGTGATCCGAG-3')

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    CR (CRISPR/Cas9-resistant)-PDHA2S293A (PDHA2 Human)
    

    Use

    Lentiviral

    Mutation

    c.321C>T (silent when translated to protein, c…

    Promoter

    EF1alpha

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pLEX307_CR-PDHA2

    Plasmid

    #115199

    Purpose

    Lentiviral transduction and expression of a CRISPR/Cas9-resistant PDHA2 into any mammalian cell (when using sgRNA 5'-ATGTAATGACGTGATCCGAG-3')

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    CR (CRISPR/Cas9-resistant)-PDHA2WT (PDHA2 Human)
    

    Use

    Lentiviral

    Mutation

    c.321C>T (silent when translated to protein, c…

    Promoter

    EF1alpha

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pLEX307_CR-PDHA2S291A

    Plasmid

    #115203

    Purpose

    Lentiviral transduction and expression of CRISPR/Cas9-resistant PDHA2S291A into any mammalian cell (when using sgRNA 5'-ATGTAATGACGTGATCCGAG-3')

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    CR (CRISPR/Cas9-resistant)-PDHA2S291A (PDHA2 Human)
    

    Use

    Lentiviral

    Mutation

    c.321C>T (silent when translated to protein, c…

    Promoter

    EF1alpha

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. lentiCRISPRv2_RB1#2

    Plasmid

    #174151

    Purpose

    Lentiviral vector expressing Cas9 and a sgRNA against the human RB1 gene

    Depositor

    Julien Sage

    Article

    Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

    Insert

    RB1 (RB1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Sept. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pHIV-NAT-FLAG-CIP2A FL (sg2R)

    Plasmid

    #222624

    Purpose

    Lentiviral vector that expresses Flag-tagged sgRNA resistant CIP2A in mammalian cells

    Depositor

    Daniel Durocher

    Article

    Adam et al Nat Cancer. 2021 Dec;2(12):1357-1371. do

    Insert

    CIP2A (CIP2A Human)
    

    Use

    Lentiviral

    Tags

    Flag

    Expression

    Mammalian

    Promoter

    EF-1-alpha promoter

    Available Since

    July 18, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

19. pPHAGE-CR-PINK1-C-TAP

    Plasmid

    #128510

    Purpose

    Lentiviral constitutive expression of CRISPR-resistant PINK1 with c-terminal FLAG and HA tag.

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    PTEN induced kinase 1 (PINK1 Human)
    

    Use

    Lentiviral

    Tags

    FLAG and HA tags

    Expression

    Mammalian

    Mutation

    Synonymous silent mutation in Q5 to render sgRNA …

    Promoter

    CMV

    Available Since

    Sept. 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pKHH030_sgRB1#1

    Plasmid

    #174144

    Purpose

    Lentiviral vector expressing a sgRNA against the human RB1 gene

    Depositor

    Julien Sage

    Article

    Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

    Insert

    RB1 (RB1 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge