We narrowed to 4,063 results for: biorxiv

1. pBK1298-AAV-EFSNC-dCjCas9-HP1bNH(111-173)

   Plasmid

   #223143

   Purpose

   Expression of truncated HP1b with dCjCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   HP1b (CBX1 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 111-173

   Promoter

   EF1a

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pBK1308-AAV-EFSNC-dSaCas9-HP1bNH(111-173)

   Plasmid

   #223153

   Purpose

   Expression of truncated HP1b with dSaCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   HP1b (CBX1 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 111-173

   Promoter

   EF1a

   Available Since

   Aug. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pBK1307-AAV-EFSNC-dSaCas9-HP1b(79-173)

   Plasmid

   #223152

   Purpose

   Expression of truncated HP1b with dSaCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   HP1b (CBX1 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 79-173

   Promoter

   EF1a

   Available Since

   Aug. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pBK1861-AAV-EFSNC-dSaCas9-KRAB-MECP2(APOE-gRNA1)

   Plasmid

   #223161

   Purpose

   Expression of KRAB and truncated MECP2 with dSaCas9 and gRNA1 targeting human/mouse APOE

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   KRAB-MECP2 (MECP2 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 204-310 (MECP2)

   Promoter

   EF1a

   Available Since

   Aug. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pBK2046-AAV-2xSp1-2xNFkB-EFSNC-dSaCas9-KRAB-MECP2(APOE-gRNA1)

   Plasmid

   #223166

   Purpose

   2nd gen. vector for expression of KRAB and truncated MECP2 with dSaCas9 and gRNA1 targeting human/mouse APOE

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   KRAB-MECP2 (MECP2 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 204-310 (MECP2)

   Promoter

   EF1a

   Available Since

   Aug. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pX330_DAZL_cterm2

   Plasmid

   #222919

   Purpose

   Cas9/sgRNA plasmid for targeting DAZL

   Depositor

   George Church

   Article

   Pierson Smela et al bioRxiv 2022.07.11.499564

   Insert

   Cas9, DAZL sgRNA 2 (DAZL Human, Synthetic)
   

   Use

   CRISPR

   Available Since

   Aug. 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pX330_DAZL_cterm3

   Plasmid

   #222920

   Purpose

   Cas9/sgRNA plasmid for targeting DAZL

   Depositor

   George Church

   Article

   Pierson Smela et al bioRxiv 2022.07.11.499564

   Insert

   Cas9, DAZL sgRNA 3 (DAZL Human, Synthetic)
   

   Use

   CRISPR

   Available Since

   Aug. 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pX330_TFAP2C_cterm

   Plasmid

   #222916

   Purpose

   Cas9/sgRNA plasmid for targeting TFAP2C

   Depositor

   George Church

   Article

   Pierson Smela et al bioRxiv 2022.07.11.499564

   Insert

   Cas9, TFAP2C sgRNA (TFAP2C Human, Synthetic)
   

   Use

   CRISPR

   Available Since

   Aug. 1, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pX330_FIGLA_cterm4

   Plasmid

   #222909

   Purpose

   Cas9/sgRNA plasmid for targeting FIGLA

   Depositor

   George Church

   Article

   Pierson Smela et al bioRxiv 2022.07.11.499564

   Insert

   Cas9, FIGLA sgRNA 4 (FIGLA Human, Synthetic)
   

   Use

   CRISPR

   Available Since

   July 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pX330_FIGLA_cterm3

    Plasmid

    #222908

    Purpose

    Cas9/sgRNA plasmid for targeting FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, FIGLA sgRNA 3 (FIGLA Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pX330_FIGLA_cterm2

    Plasmid

    #222907

    Purpose

    Cas9/sgRNA plasmid for targeting FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, FIGLA sgRNA 2 (FIGLA Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pX330_FIGLA_cterm1

    Plasmid

    #222906

    Purpose

    Cas9/sgRNA plasmid for targeting FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, FIGLA sgRNA 1 (FIGLA Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pX330_NANOS3_cterm

    Plasmid

    #222904

    Purpose

    Cas9/sgRNA plasmid for targeting NANOS3

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, NANOS3 sgRNA (NANOS3 Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pPB-cT3G-cERP2-FIGLA

    Plasmid

    #222929

    Purpose

    PiggyBac transposon plasmid for doxycycline inducible expression of FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    FIGLA (FIGLA Human)
    

    Expression

    Mammalian

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pPB-cT3G-cERP2-HHEX

    Plasmid

    #222928

    Purpose

    PiggyBac transposon plasmid for doxycycline inducible expression of HHEX

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    HHEX (HHEX Human)
    

    Expression

    Mammalian

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pPB-cT3G-cERP2-DLX5

    Plasmid

    #222927

    Purpose

    PiggyBac transposon plasmid for doxycycline inducible expression of DLX5

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    DLX5 (DLX5 Human)
    

    Expression

    Mammalian

    Available Since

    July 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pPB-cT3G-cERH-LHX8

    Plasmid

    #222921

    Purpose

    PiggyBac transposon plasmid for doxycycline inducible expression of LHX8

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    LHX8 (LHX8 Human)
    

    Expression

    Mammalian

    Available Since

    July 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. LacI pm

    Plasmid

    #218097

    Purpose

    Phagemid that expresses LacI but no phage proteins, used as a control

    Depositor

    Kevin Esvelt

    Type

    Empty backbone

    Expression

    Bacterial

    Available Since

    May 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pAAV-U6-sgCTG-CMV-GFP

    Plasmid

    #216734

    Purpose

    AAV plasmid containing sgCTG (target sequence: (CUG)6) driven by a U6 promoter and eGFP under the control of the CMV promoter. Used for in vivo experiments.

    Depositor

    Vincent Dion

    Article

    Alvaro et al bioRxiv

    Insert

    sgCTG
    

    Use

    AAV and CRISPR

    Expression

    Mammalian

    Promoter

    U6 and CMV

    Available Since

    April 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-nEF-SpCas9D10A nickase

    Plasmid

    #216736

    Purpose

    Expresses SpCas9-D10A nickase from a nEF promoter. For AAV packaging. Derived from pAAV-nEF-SpCas9 (Addgene #87115)

    Depositor

    Vincent Dion

    Article

    Alvaro et al bioRxiv

    Insert

    Cas9-D10A nickase
    

    Use

    AAV and CRISPR

    Expression

    Mammalian

    Mutation

    D10A

    Promoter

    EF-1-alpha core

    Available Since

    April 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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