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LentiCrispr V2 Elovl5 sgRNA1

Plasmid

#258337

Purpose

Crispr mediated knockout of Elovl5 gene

Depositor

Xiaoai Zhao

Publication

Zhao et al Sci Adv. 2026 Jul 31;12(31):eaeh9771. do

Insert

sgRNA1 targeting Elovl5 (Elovl5 Mouse)

Use

CRISPR and Lentiviral

Available since

July 7, 2026

Availability

Academic Institutions and Nonprofits only

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pLKO H2BmRFP-2A-Plgrkt K147R v4 trcr filler

Plasmid

#256783

Purpose

lentiviral construct with H2BmRFP-2A-Plgrkt (mouse) K147R and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI.

Depositor

Daniel Schramek

Publication

Al-Zahrani et al Nature. 2026 Jul 8. doi: 10.1038/s41586-

Insert

Plgrkt (Plgrkt Mouse)

Use

Lentiviral

Mutation

K147R

Available since

June 22, 2026

Availability

Academic Institutions and Nonprofits only

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pX459-Itgav gRNA

Plasmid

#246576

Purpose

CRISPR vector co-expressing Cas9 and a mouse Itgav gRNA

Depositor

Mario Vallon

Publication

Heiden et al J Biol Chem. 2025 Sep 4:110682. doi: 10.

Insert

Itgav gRNA (Itgav Mouse)

Use

CRISPR

Promoter

U6

Available since

Oct. 23, 2025

Availability

Academic Institutions and Nonprofits only

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CA-0045 CMVTO-mono-hIL10 (R5A11M)

Plasmid

#231190

Purpose

Mutant human IL-10 monomer

Depositor

Xiaojing Gao

Publication

Aldrete et al Nat Chem Biol. 2025 Jan 15. doi: 10.1038

Insert

mono-hIL10 (R5A11M) (IL10 Human)

Expression

Mammalian

Mutation

N36I, N110I, K117N, F129L

Available since

Jan. 24, 2025

Availability

Academic Institutions and Nonprofits only

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SFFV-TOX2-Brd 402

Plasmid

#219325

Purpose

Transcription factor TOX2 with a specific barcode assigned.

Depositor

Filipe Pereira

Publication

Kurochkin et al Cell Syst. 2026 Jan 21;17(1):101457. doi

Insert

TOX2 (TOX2 Human)

Use

Lentiviral

Promoter

The spleen focus-forming virus (SFFV) promoter

Available since

Oct. 15, 2024

Availability

Academic Institutions and Nonprofits only

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pDest17_hnRNPA1_YtoW

Plasmid

#224253

Purpose

Bacterial expression of N-terminally 6His-tagged hnRNPA1_YtoW

Depositor

Tanja Mittag

Publication

Alshareedah et al Nat Phys. 2024 Sep;20(9):1482-1491. doi:

Insert

hnRNPA1_YtoW (HNRNPA1 Human)

Tags

6xHis

Expression

Bacterial

Mutation

Y52W, Y59W, Y75W, Y81W, Y110W, Y120W, Y129W

Promoter

T7

Available since

Aug. 26, 2024

Availability

Academic Institutions and Nonprofits only

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pAAV-cTNT-NEXN-GFP

Plasmid

#216835

Purpose

cardiomyocytes-specific plasmid, expressing the coding sequence of mouse Nexn and GFP tag

Depositor

Yuxuan Guo

Publication

Guo et al Acta Pharmacol Sin. 2024 Jul 23. doi: 10

Insert

Nexn (mus musculus) (Nexn Mouse)

Use

AAV

Tags

GFP

Available since

Aug. 8, 2024

Availability

Academic Institutions and Nonprofits only

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pX330_SAFBgRNA8

Plasmid

#196103

Purpose

Contains guide RNA to 3' end of mouse SAFB gene for safb1/2 dko. Used with Addgene IDs: 196106, 196107, 196108

Depositor

Mauro Calabrese

Publication

Cherney et al RNA. 2023 Jul 19:rna.079569.122. doi: 10

Insert

SAFB (Safb Mouse)

Use

CRISPR and Mouse Targeting

Expression

Bacterial and Mammalian

Available since

Sept. 5, 2023

Availability

Academic Institutions and Nonprofits only

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pnEA-NpM-Dm4E-T_9-21-GB1_Z

Plasmid

#148174

Purpose

Bacterial Expression of Dm4E-T_9-21

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T_9-21 (4E-T Fly)

Expression

Bacterial

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pnEA-NpM-Dm4E-T_9-44-GB1_Z

Plasmid

#148175

Purpose

Bacterial Expression of Dm4E-T_9-44

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T_9-44 (4E-T Fly)

Expression

Bacterial

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pnEA-NpM-Dm4E-T_21-44-GB1_Z

Plasmid

#148176

Purpose

Bacterial Expression of Dm4E-T_21-44

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T_21-44 (4E-T Fly)

Expression

Bacterial

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pnEA-NvG-Dm4E-T_1-58_Z

Plasmid

#148182

Purpose

Bacterial Expression of Dm4E-T_1-58

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T_1-58 (4E-T Fly)

Expression

Bacterial

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pnEA-NvM-Dm4E-T_1-58_Z

Plasmid

#148185

Purpose

Bacterial Expression of Dm4E-T_1-58

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T_1-58 (4E-T Fly)

Expression

Bacterial

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pnEA-NvM-Dm4E-T_1-58-Y10AL15A_Z

Plasmid

#148187

Purpose

Bacterial Expression of Dm4E-T_1-58-Y10AL15A

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T_1-58-Y10AL15A (4E-T Fly)

Expression

Bacterial

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pAc5.1B-EGFP-Dm4E-T-del28-43_T

Plasmid

#147601

Purpose

Insect Expression of Dm4E-T-del28-43

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T-del28-43 (4E-T Fly)

Expression

Insect

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pAc5.1B-EGFP-Dm4E-T-del312-356_T

Plasmid

#147602

Purpose

Insect Expression of Dm4E-T-del312-356

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T-del312-356 (4E-T Fly)

Expression

Insect

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pAc5.1B-lambdaN-HA-Dm4E-T_1-738_T

Plasmid

#147608

Purpose

Insect Expression of Dm4E-T_1-738

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T_1-738 (4E-T Fly)

Expression

Insect

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pAc5.1B-lambdaN-HA-Dm4E-T-del28-43_T

Plasmid

#147609

Purpose

Insect Expression of Dm4E-T-del28-43

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T-del28-43 (4E-T Fly)

Expression

Insect

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pAc5.1B-lambdaN-HA-Dm4E-T-del312-356_T

Plasmid

#147610

Purpose

Insect Expression of Dm4E-T-del321-356

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T-del321-356 (4E-T Fly)

Expression

Insect

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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pAc5.1B-EGFP-Dm4E-T-del739-1010_T

Plasmid

#147576

Purpose

Insect Expression of Dm4E-T-del739-1010

Depositor

Elisa Izaurralde

Publication

Igreja et al Nat Commun. 2014 Sep 2;5:4790. doi: 10.1

Insert

Dm4E-T-del739-1010 (4E-T Fly)

Expression

Insect

Available since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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