Aneuploidy selects for the acquisition of driver genes in breast cancer.
Al-Zahrani KN, Langille ER, Nurtanto J, Obersterescu A, Teng K, Lowden C, Dessapt J, Chiu CH, Caldwell LV, Cook DP, Perez-Castro MA, Berman JM, Tsai R, Bahcheli AT, Mbamalu G, Wu S, Narimatsu M, Lopes AG, Fotiadou I, Chan K, Zhang L, Bang KWA, Parsons MJ, Mourao L, Temel EI, McCulla L, Sravya P, Zhang L, Sajjakulnukit P, Lyssiotis CA, Borowsky AD, Scheele CLGJ, Wahl DR, Jackson HW, Stewart KS, Fuchs E, Egan SE, Pujana MA, Reimand J, Wrana JL, Schramek D
Nature. 2026 Jul 8. doi: 10.1038/s41586-026-10752-9.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 256774 | pLKO Cre v4 trcr filler | lentiviral construct with Cre recombinase and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256775 | pLKO H2BmRFP-2A-puro v4 trcr filler | lentiviral construct with H2BmRFP-2A-puromycin and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256776 | pXPR502 PPH-Cre v14 trcr filler | lentiviral construct with PPH-Cre recombinase (P65-PP7 Coat Protein-HSF1-Cre) U6 driven gRNA cassette with the v14 modified trcrRNA. gRNAs can be cloned in by digesting the filler with SapI. |
| 256777 | pXPR502 PPH-puro v14 trcr filler | lentiviral construct with PPH-Puro (P65-PP7 Coat Protein-HSF1-Puro) U6 driven gRNA cassette with the v14 modified trcrRNA. gRNAs can be cloned in by digesting the filler with SapI. |
| 256778 | pXPR502 PPH-Cre dual trcrs filler | lentiviral construct with PPH-Cre recombinase (P65-PP7 Coat Protein-HSF1-Cre) U6 driven gRNA cassettes with the v4 and v14 modified trcrRNAs. gRNAs can be cloned in with SapI/BsmBI. |
| 256779 | pLV PPH-GFP | lentiviral construct with PPH-GFP (P65-PP7 Coat Protein-HSF1-GFP) |
| 256780 | pXPR502 H2BmRFP-2A-puro v14 trcr filler | lentiviral construct with H2BmRFP-2A-puromycin and U6 driven gRNA cassette with the v14 modified trcrRNA. gRNAs can be cloned in by digesting the filler with SapI. |
| 256781 | pLKO H2BmRFP-2A-PLGRKT v4 trcr filler | lentiviral construct with H2BmRFP-2A-PLGRKT (human) and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256782 | pLKO H2BmRFP-2A-Plgrkt v4 trcr filler | lentiviral construct with H2BmRFP-2A-Plgrkt (mouse) and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256783 | pLKO H2BmRFP-2A-Plgrkt K147R v4 trcr filler | lentiviral construct with H2BmRFP-2A-Plgrkt (mouse) K147R and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256784 | pLKO H2BmRFP-2A-Plgrkt Δ139-147 v4 trcr filler | lentiviral construct with H2BmRFP-2A-Plgrkt (mouse) Δ139-147 and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256785 | pLKO H2BmRFP-2A-puro HA v4 trcr filler | lentiviral construct with H2BmRFP-2A-puromycin, HA, and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256786 | pLKO H2BmRFP-2A-puro Plgrkt v4 trcr filler | lentiviral construct with H2BmRFP-2A-puromycin, Plgrkt, and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256787 | pLKO H2BmRFP-2A-puro Plgrkt-HA v4 trcr filler | lentiviral construct with H2BmRFP-2A-puromycin, Plgrkt-HA, and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256788 | pLKO H2BmRFP-2A-puro PLGRKT v4 trcr filler | lentiviral construct with H2BmRFP-2A-puromycin, PLGRKT, and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256789 | pLKO HA-2A-Cre v4 trcr filler | lentiviral construct with HA-2A-Cre recombinase and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256790 | pLKO Cre-2A-Plgrkt v4 trcr filler | lentiviral construct with Cre recombinase-2A-Plgrkt and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256791 | pLKO Cre-2A-Plgrkt K147R v4 trcr filler | lentiviral construct with Cre recombinase-2A-Plgrkt K147R and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |
| 256792 | pLKO Cre-2A-Plgrkt Δ139-147 v4 trcr filler | lentiviral construct with Cre recombinase-2A-Plgrkt Δ139-147 and U6 driven gRNA cassette with the v4 modified trcrRNA. gRNAs can be cloned in by digesting the filler with BsmBI. |