We narrowed to 579 results for: hyper

1. B52_puro_gRNA_3418711_KCNB2

   Plasmid

   #197558

   Purpose

   gRNA targeting upstream region of KCNB2 (site 3418711, control for epigenetic targeting)

   Depositor

   Darius Bägli

   Insert

   upstream KCNB2 promoter gRNA (Kcnb2 Rat)
   

   Use

   Grna with puromycin selection

   Tags

   puromycin resistance cassette under CMV promotion

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   March 27, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. pcDNA3.1-Flag-PGC-1alpha1

   Plasmid

   #45501

   Depositor

   Jorge Ruas, Bruce Spiegelman

   Article

   Ruas et al Cell. 2012 Dec 7;151(6):1319-31. doi: 10

   Insert

   PGC-1alpha Isoform1 (Ppargc1a Mouse)
   

   Tags

   6xHis and Flag

   Expression

   Mammalian

   Mutation

   Q339K relative to NM_008904

   Available Since

   Aug. 9, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-CAG-mCherry-Tandem-PSAM4-GlyR

   Plasmid

   #208361

   Purpose

   Expression of the inhibitory chemogenetic tool PSAM4-GlyR and mCherry reporter. Application of ultrapotent agonists induces neuronal silencing.

   Depositor

   David Bennett

   Article

   Perez-Sanchez et al Sci Transl Med. 2023 Oct 4;15(716):eadh3

   Insert

   mCherry-TANDEM-PSAM4-GlyR
   

   Use

   AAV

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   Oct. 13, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pSPL3-ABCC8-2

   Plasmid

   #135916

   Purpose

   Encodes ABCC8 exon 2 wild type for the analysis of splicing variants

   Depositor

   Diana Valverde Pérez

   Article

   Lago-Docampo et al Sci Rep. 2020 Sep 15;10(1):15135. doi: 1

   Insert

   ATP-binding Cassette subfamily C member 8 (ABCC8 Human)
   

   Use

   Exon trapping

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   March 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pSPL3-ABCC8-9-10

   Plasmid

   #135918

   Purpose

   Encodes ABCC8 exons 9 and 10 wild type for the analysis of splicing variants

   Depositor

   Diana Valverde Pérez

   Article

   Lago-Docampo et al Sci Rep. 2020 Sep 15;10(1):15135. doi: 1

   Insert

   ATP-binding Cassette subfamily C member 8 (ABCC8 Human)
   

   Use

   Exon trapping

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   March 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pMXS-IRES-Blast POLE1 N-ISCmut

   Plasmid

   #160803

   Purpose

   Express N-terminal ISC mutant POLE1

   Depositor

   Richard Possemato

   Article

   Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

   Insert

   POLE1 N-ISCmut (POLE Human)
   

   Use

   Retroviral

   Tags

   3xFLAG

   Mutation

   shPOLE_1 and shPOLE2 resistant, C651S, C654S, C66…

   Available Since

   Jan. 20, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pMXS-IRES-Blast POLE1 C-ISCmut

   Plasmid

   #160804

   Purpose

   Express C-terminal ISC mutant POLE1

   Depositor

   Richard Possemato

   Article

   Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

   Insert

   POLE1 C-ISCmut (POLE Human)
   

   Use

   Retroviral

   Tags

   3xFLAG

   Mutation

   shPOLE_1 and shPOLE2 resistant, C2221S, C2224S, C…

   Available Since

   Oct. 30, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pSPL3-ABCC8-27

   Plasmid

   #135919

   Purpose

   Encodes ABCC8 exon 27 wild type for the analysis of splicing variants

   Depositor

   Diana Valverde Pérez

   Article

   Lago-Docampo et al Sci Rep. 2020 Sep 15;10(1):15135. doi: 1

   Insert

   ATP-binding Cassette subfamily C member 8 (ABCC8 Human)
   

   Use

   Exon trapping

   Expression

   Mammalian

   Promoter

   SV40

   Available Since

   March 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pcDNA3.1-Flag-PGC-1alpha2

   Plasmid

   #45502

   Depositor

   Jorge Ruas, Bruce Spiegelman

   Article

   Ruas et al Cell. 2012 Dec 7;151(6):1319-31. doi: 10

   Insert

   PGC-1alpha Isoform2 (Ppargc1a Mouse)
   

   Tags

   6xHis and Flag

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Aug. 9, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pMXS-IRES-Blast POLD1 ISCmut

    Plasmid

    #160806

    Purpose

    Express ISC mutant POLD1

    Depositor

    Richard Possemato

    Article

    Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

    Insert

    POLD1 ISCmut (POLD1 Human)
    

    Use

    Retroviral

    Mutation

    Codon optimized C-terminal 230 amino acids, C1058…

    Available Since

    Oct. 30, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. pMXS-IRES-Blast POLA1 ISCmut

    Plasmid

    #160808

    Purpose

    Express ISC mutant POLA1

    Depositor

    Richard Possemato

    Article

    Sviderskiy et al Mol Cell. 2020 Oct 28. pii: S1097-2765(2

    Insert

    POLA1 ISCmut (POLA1 Human)
    

    Use

    Retroviral

    Mutation

    Codon optimized, C1354S, C1359S, C1377S, C1380S

    Available Since

    Oct. 30, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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12. R703-M72-303: CMV51p> Halotag-Hs.KRAS4b

    Plasmid

    #159679

    Purpose

    Mammalian protein expression of KRAS4b-Halotag fusion

    Depositor

    Dominic Esposito

    Article

    Goswami et al Elife. 2020 Jan 20;9. pii: 47654. doi: 1

    Insert

    Halotag-Hs.KRAS4b (KRAS Human)
    

    Tags

    Halotag

    Expression

    Mammalian

    Available Since

    Sept. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. R713-M88-303: CMV51p> Halotag-Hs.HRAS

    Plasmid

    #159681

    Purpose

    Mammalian protein expression of HRAS-Halotag fusion

    Depositor

    Dominic Esposito

    Article

    Goswami et al Elife. 2020 Jan 20;9. pii: 47654. doi: 1

    Insert

    Halotag-Hs.HRAS (HRAS Human)
    

    Tags

    Halotag

    Expression

    Mammalian

    Available Since

    Sept. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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14. R713-M91-303: CMV51p> Halotag-Hs.NRAS

    Plasmid

    #159682

    Purpose

    Mammalian protein expression of NRAS-Halotag fusion

    Depositor

    Dominic Esposito

    Article

    Goswami et al Elife. 2020 Jan 20;9. pii: 47654. doi: 1

    Insert

    Halotag-Hs.NRAS (NRAS Human)
    

    Tags

    Halotag

    Expression

    Mammalian

    Available Since

    Sept. 29, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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15. pTripz NEO DEST

    Plasmid

    #209072

    Purpose

    Modified DOX-ON inducible destination vector with a c-terminal 3X flag tag to be used for LR recombination reactions to inducibly express cDNAs of interest

    Depositor

    Matthew Oser

    Article

    Oser et al Cancer Discov. 2019 Feb;9(2):230-247. do

    Type

    Empty backbone

    Use

    Lentiviral; Gateway destination vector to be used…

    Tags

    3X FLAG

    Promoter

    CMV

    Available Since

    Nov. 13, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. R713-M85-303: CMV51p> Halotag-Hs.KRAS4a

    Plasmid

    #159680

    Purpose

    Mammalian protein expression of KRAS4a-Halotag fusion

    Depositor

    Dominic Esposito

    Article

    Goswami et al Elife. 2020 Jan 20;9. pii: 47654. doi: 1

    Insert

    Halotag-Hs.KRAS4a (KRAS Human)
    

    Tags

    Halotag

    Expression

    Mammalian

    Available Since

    Oct. 5, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. pTripZ EV

    Plasmid

    #209071

    Purpose

    DOX-ON inducible expression vector that has a stuffer sequence after an LR reaction and used as empty expression vector control

    Depositor

    Matthew Oser

    Article

    Oser et al Cancer Discov. 2019 Feb;9(2):230-247. do

    Insert

    stuffer DNA sequence after LR recombination with pTripZ NEO DEST to be used as an empty vector control
    

    Use

    Lentiviral

    Tags

    3XFLAG

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 25, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. HisGB1-CITED2(216-269)+CBPTAZ1(340-439)

    Plasmid

    #173761

    Purpose

    Bacterial coexpression of human CITED2 CTAD with CBP TAZ1

    Depositor

    Peter Wright

    Article

    Berlow et al Nature. 2017 Mar 16;543(7645):447-451. d

    Inserts

    CITED2 (216-269) (CITED2 Human)
    CBP TAZ1 (340-439) (Crebbp Mouse)
    

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    Feb. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pYY166 pcDNA3.4-His-MBP-hAID

    Plasmid

    #231942

    Purpose

    Expression of His-MBP-AID fusion protein in mammalian cells

    Depositor

    Fei-Long Meng

    Article

    Wang et al Cell. 2023 May 11;186(10):2193-2207.e19.

    Insert

    AID (AICDA Human)
    

    Tags

    His-MBP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 21, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pTripZ RB1 WT-3XFLAG

    Plasmid

    #209070

    Purpose

    DOX-ON inducible expression vector that expresses RB1 WT with c-terminal 3X flag tag

    Depositor

    Matthew Oser

    Article

    Oser et al Cancer Discov. 2019 Feb;9(2):230-247. do

    Insert

    human RB1 WT after LR recombination with pTripZ NEO DEST to inducibly express RB1 WT with a c-terminal 3X flag tag
    

    Use

    Lentiviral

    Tags

    3XFLAG

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 25, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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