We narrowed to 730 results for: KO

1. sgRNA TR KO 2

   Plasmid

   #207610

   Purpose

   sgRNA 2 to knockout TR by replacement with a PuroR cassette

   Depositor

   Jens Schmidt

   Article

   Klump et al Cell Rep. 2023 Jun 1;42(6):112577. doi:

   Insert

   TCAGGCCGCAGGAAGAGGAA
   

   Use

   Tags

   None

   Expression

   Mammalian

   Mutation

   Promoter

   CMV and U6

   Available since

   April 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pPB-hVASA-KO-WPRE

   Plasmid

   #214124

   Purpose

   Gene expression by Piggybac transposase in mammalian cells

   Depositor

   Sho Yoshimatsu

   Insert

   hKO
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Codon-optimized for mammalian cells

   Promoter

   Available since

   April 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. SHLD3 KO sgRNA #2

   Plasmid

   #207106

   Purpose

   pX330 based plasmid for expression of Cas9 and the CTGAAGGAACAGACTAATTC sgRNA to target the SHLD3 locus..

   Depositor

   Jens Schmidt

   Article

   Heyza et al Elife. 2023 Jun 21;12:e87086. doi: 10.75

   Insert

   CTGAAGGAACAGACTAATTC
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV and U6

   Available since

   March 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. sgRNA TR KO 1

   Plasmid

   #207609

   Purpose

   sgRNA 1 to knockout TR by replacement with a PuroR cassette

   Depositor

   Jens Schmidt

   Article

   Klump et al Cell Rep. 2023 Jun 1;42(6):112577. doi:

   Insert

   ACCCTAACTGAGAAGGGCGT
   

   Use

   Tags

   None

   Expression

   Mammalian

   Mutation

   Promoter

   CMV and U6

   Available since

   March 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. px459-Daxx KO sgRNA

   Plasmid

   #186939

   Purpose

   Daxx KO in mouse ES cells

   Depositor

   Zhiguo Zhang

   Article

   Xu et al Nat Commun. 2022 May 6;13(1):2514. doi:

   Insert

   Daxx KO sgRNA (Daxx Mouse)
   

   Use

   CRISPR and Mouse Targeting

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Aug. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. px459-Pole4 KO sgRNA

   Plasmid

   #186935

   Purpose

   Pole4 KO in mouse ES cells

   Depositor

   Zhiguo Zhang

   Article

   Xu et al Nat Commun. 2022 May 6;13(1):2514. doi:

   Insert

   Pole4 KO sgRNA (Pole4 Mouse)
   

   Use

   CRISPR and Mouse Targeting

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Aug. 5, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. px459-Pole3 KO sgRNA

   Plasmid

   #186934

   Purpose

   Pole3 KO in mouse ES cells

   Depositor

   Zhiguo Zhang

   Article

   Xu et al Nat Commun. 2022 May 6;13(1):2514. doi:

   Insert

   Pole3 KO sgRNA (Pole3 Mouse)
   

   Use

   CRISPR and Mouse Targeting

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Aug. 5, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLentiCRISPRv2-POLB-KO-g1

   Plasmid

   #176090

   Purpose

   Cas9 plus POLB gRNA #1; contains a puromycin resistance cassette

   Depositor

   Robert Sobol

   Article

   Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

   Insert

   POLB sgRNA #1 (POLB Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Jan. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. EED-KO-gRNA-2

   Plasmid

   #131322

   Purpose

   gRNA to knockout EED. Use with EED-KO-gRNA-1

   Depositor

   Danny Reinberg

   Article

   Oksuz et al Mol Cell. 2018 Jun 21;70(6):1149-1162.e5

   Insert

   EED-KO-gRNA-2
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 6, 2020

   Availability

   Academic Institutions and Nonprofits only

10. EED-KO-gRNA-1

    Plasmid

    #131321

    Purpose

    gRNA to knockout EED. Use with EED-KO-gRNA-2

    Depositor

    Danny Reinberg

    Article

    Oksuz et al Mol Cell. 2018 Jun 21;70(6):1149-1162.e5

    Insert

    EED-KO-gRNA-1
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 6, 2020

    Availability

    Academic Institutions and Nonprofits only

11. SOX2 KO (T2A-H2B-EGFP)

    Plasmid

    #167969

    Purpose

    SOX2 CDS replacement with T2A-H2B-EGFP

    Depositor

    Emma Rawlins

    Article

    Sun et al eLife. 2021 Oct 6;10. pii: 67886. doi: 1

    Insert

    SRY-Box Transcription Factor 2 (SOX2 Human)
    

    Use

    CRISPR; Donor template

    Tags

    H2B-EGFP

    Expression

    Mammalian

    Mutation

    homology arms contain point mutations to disrupt …

    Promoter

    Available since

    June 7, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. 14-3-3 KO vector

    Plasmid

    #16551

    Depositor

    Bert Vogelstein

    Article

    Chan et al Nature. 1999 Oct 7. 401(6753):616-20.

    Insert

    14-3-3 knockout (SFN Human)
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    March 27, 2008

    Availability

    Academic Institutions and Nonprofits only

13. pLenti Puro HA-Ubiquitin-KO

    Plasmid

    #236292

    Purpose

    Lentiviral vector expressing HA-tagged ubiquitin KO mutant

    Depositor

    Melina Fan, Addgene Research Program

    Insert

    Ubiquitin KO (UBB Human)
    

    Use

    Lentiviral

    Tags

    HA

    Expression

    Mutation

    Single ubiquitin coding sequence containing KO mu…

    Promoter

    CMV

    Available since

    April 15, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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14. pHBS952 TARDBP-Exon1-ko-sgRNA1-SpCas9

    Plasmid

    #107857

    Purpose

    To knock-out TDP43

    Depositor

    Rajat Rohatgi

    Article

    Schmidt et al Nat Commun. 2019 Oct 25;10(1):4890. doi:

    Insert

    gRNA against TARDBP (Exon 1) (TARDBP Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    June 1, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. pHBS953 TARDBP-Exon2-ko-sgRNA2-SpCas9

    Plasmid

    #107858

    Purpose

    To knock-out TDP43

    Depositor

    Rajat Rohatgi

    Article

    Schmidt et al Nat Commun. 2019 Oct 25;10(1):4890. doi:

    Insert

    gRNA against TARDBP (Exon 2) (TARDBP Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    June 1, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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16. pIDTsmart-RC2-KO-delVP1-VP1-588TAG

    Plasmid

    #240123

    Purpose

    Express AAV2-KO (R585A,R588A) capsid with ncAA mutant at site 588 of VP1

    Depositor

    Abhishek Chatterjee

    Article

    Pham et al bioRxiv 2024.07.20.604406

    Inserts

    RC2-DelVP1-R585,588A
    VP1-588-TAG
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    July 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pIDTsmart-RC2-KO-delVP1-VP1-454TAG

    Plasmid

    #240062

    Purpose

    Express AAV2-KO (R585A,R588A) capsid with ncAA mutant at site 454 of VP1

    Depositor

    Abhishek Chatterjee

    Article

    Erickson et al Bioconjug Chem. 2024 Jan 17;35(1):64-71.

    Inserts

    RC2-DelVP1-R585,588A
    VP1-454-TAG-R585,588A
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    June 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. PX459-CTNNA1(α-catenin CRISPR KO)

    Plasmid

    #229708

    Purpose

    Knockout of a-catenin in mammalian cells using CRISPR-Cas9 technology

    Depositor

    Alpha Yap

    Article

    Noordstra et al Dev Cell. 2023 Sep 25;58(18):1748-1763.e

    Insert

    CTNNA1 (alpha-catenin) Human (CTNNA1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV promoter

    Available since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pHnS KI;Pdha1 Donor;3xV5 KO;Mff

    Plasmid

    #240301

    Purpose

    KI:Pdha1 Donor:3xV5 KO:MFF

    Depositor

    Yuki Ogawa

    Insert

    KI gRNA for Pdha1
    

    Use

    AAV

    Tags

    Expression

    Mutation

    NA

    Promoter

    Available since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pHnS KI;Actb Donor;3xV5 KO;Template

    Plasmid

    #240291

    Purpose

    KI:Actb Donor:3xV5 KO:Template

    Depositor

    Yuki Ogawa

    Insert

    KI gRNA for Actb
    

    Use

    AAV

    Tags

    Expression

    Mutation

    NA

    Promoter

    Available since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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