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Learn how to use Easi-CRISPR to generate mouse knock-in and conditional allele models.

Discover the tools you need to perform plant genome engineering with CRISPR.

Three studies recently showed that CRISPR can be used to treat Duchenne muscular dystrophy in mice. Learn about the work and obstacles to application.

Learn what non-model organisms are, why scientists use them, and what they can teach us.

Long-read sequencing has allowed researchers to identify plasmid dimers and multimers. Learn about them - and how to troubleshoot - in this blog post.

Learn about the sources of spontaneous recombination and optimizing Cre-recombinase dependent AAV vector expression in vivo.

Take a look at the developments in genome engineering throughout history and the parallels in science fiction.

Learn about some of the factors you should take into consideration when choosing the appropriate AAV for your next experiment.

Protocol to generate stable cell lines expressing a gene of interest from an integrated lentiviral vector.

Description of Polymerase Chain Reaction with protocol, tips and FAQ

Learn how to select the plasmid purification kit that best suits your needs!

Adeno-associated virus (AAV) vector serotypes can help you target specific cell types through their tissue tropism.

Get perspectives and possibilities for future action from scientists and other citizens who participated in the March for Science.

This protocol describes the basic steps for lysing cells, determining total protein concentration in the lysate, running a precast SDS-PAGE gel, and immunoblotting.

Ready to let your tags do the work for you? Learn about self-labelling protein tags and how they can give you flexibility in your experimental approach!

Need help with the plasmid deposit process at Addgene? Consult this post for an in-depth walk through the entire process.

Learn about the csRNP epitope tagging method - a new and efficient way to tag endogenous genes using CRISPR.

This protocol describes how to run an indirect ELISA against a purified antigen to demonstrate the expected antibody dose response.

Learn how stem cell researchers use reprogramming and transdifferentiation techniques to convert cells from one type into another.

A deep dive into qPCR with a focus on analysis, chemistries, and bench tips.