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Chonnettia Jones, Addgene's executive director, reflects on 2023 and shares some of Addgene's plans for 2024.

In this episode of the Addgene podcast, learn what it was like to get Addgene off the ground and what the founders hope to see in the repository’s future.

Learn how to produce, purify, and titer adenoviral vectors for your research.

Curious about how you can expand the number and type of amino acids available in your experiment? Genetic code expansion can help!

R bodies are tiny, tunable molecule machines that can be used to break membranes. Learn all about them and their potential uses here.

Overview of polycistronic glycine tRNA-gRNA (PTG) multiplexing gRNA cassettes, with comparisons to Pol III and Cys4 gRNA cassettes.

Neil McKenna and Bert O’Malley of the Nuclear Receptor Signaling Atlas (NURSA) provide an introduction to nuclear receptors and more.

Vectors containing the piggyBac transposon are now available at Addgene. Learn how these unique tools can be used for genome engineering!

Update from the 2014 annual meeting of the Society for Neuroscience (SFN14) in Washington, D.C. as seen from the Addgene booth.

Cas13a is an RNA cleaving enzyme that can be used to detect specific RNAs. Learn about this and other applications, like nucleic acid detection.

Rationally engineered Cas9 variants eSpCas9 SpCas9-HF1 enhance CRISPR on-target specificity. Learn how in this post.

This post describes the biology and use of integrase-deficient lentiviral vectors in comparison to standard lentiviral vectors.

Joining the popular sacB counterselection method is a new suite of toxin-based allelic exchange vector that can be used in many proteobacterial genomes.

Model organisms are species that are widely studied because they are easy to maintain and modify in the lab. Common model organisms include the mouse, the fruit fly, yeast, zebrafish, and the worm.

Learn about recently available viral vectors and viral vectors coming soon from Addgene's viral service including calcium sensors, GABA sensors, voltage sensors, and control AAV.

This blog post describes a a self-excising cassette that can be used with CRISPR/Cas9 tools in C. elegans to generate genomic modifications.

Overview of the CRISPRi system for rewiring metabolic circuitry, with a focus on the paper by Zalatan et al 2015.

Interview with Ed Boyden discussing his newest optogenetics tools and the questions that motivate neuroengineering.

In this episode of the Addgene Podcast, learn all about research in Singapore and the genome engineering tools being developed in Wei Leong Chew's Lab.

Addgene supports rare disease research with the 2020 BeHEARD Awards. Read about the winners and their research in this blog post.