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A review of the types of engineered biosensors and how viruses can be used to deliver them.

FlipGFP is a genetically encoded caspase reporter that contains a flipped beta strand of GFP. There is no fluorescence unless the caspase cuts the cleavage site between the strands.

Interview with Professors Eric Mendenhall and Richard Myers about their CRISPR- based system for tagging any endogenous gene of interest.

Learn about the many ways you can deliver reprogramming factors to generate induced pluripotent stem cells (IPSCs).

There are many tools available for studying the microbiome. Learn about plasmid tools for engineering gut microbes, detection, and synthetic biology.

Learn about science writing in this post of our careers in science communication series.

Check out how you can use digital PCR to validate your CRISPR genome edits.

Find the latest plasmids and viral vectors to available at Addgene in the October 2020 hot plasmids blog post!

Use the deposit spreadsheet to quickly deposit multiple plasmids with Addgene.

Find information on CRISPR mammalian expression systems and delivery methods. Use the table to quickly compare between the methods.

Check out all of the plasmids featured in our hot plasmids articles from 2017.

Where did plasmids come from? Learn more about natural plasmids, the benefits they offer cells, and how scientists have adapted them into laboratory tools.

Learn about the different types of stem cells in this guide. In particular, we discuss the pros and cons of using embryonic stem cells and adult stem cells and using induced pluripotent stem cells (iPSCs) as a model for regenerative medicine.

Learn about different molecular cloning techniques, focusing on seven common cloning methods.

This post provides tips for designing a prime editing experiment, from pegRNA design, PE tool selection, and choice of DNA sequence to edit.

PRIDICT 2.0 is an updated software that can help you design gRNAs for PRIME editing. Read more in our guest post!

Chromoproteins are a subset of the fluorescent protein family. They give strong color in visible light and can be used for molecular biology experiments.

Learn about aptamer-based fluorphores and how they can be used to brighten up your experiments.

Curious about what's new in the Addgene repository this spring? Check out our latest Hot Plasmids post!

Learn how you can use adeno-associated viruses (AAV) for genome editing - whether combined with nucleases or not. Also, read about the advantages and disadvantages of using AAV vs. CRISPR.