...AAV-mDlx-jGCaMP8s-WPRE  AAV9 Biosensor Looger New serotype AAV-hSyn-Soma-jGCaMP8s AAV9 Biosensor Fyhn New...AAV-hSyn-Soma-jGCaMP8f AAV9 Biosensor Fyhn New serotype pAAV-hSyn-JEDI-2P-Kv-WPRE AAV9 Biosensor St-Pierre...pAAV-hSyn-JEDI-2P-WPRE AAV9 Biosensor St-Pierre New viral vector pAAV-CAG-RdLight1 AAV9 Biosensor Tian New...pAAV-hSynapsin1-RdLight1 AAV9 Biosensor Tian New viral vector pAAV_hSynapsin_psychLight2 AAV9 Biosensor Tian ...pAAV.hSynapsin.SF-iGluSnFR.A184S AAV9 Biosensor Looger New serotype pAAV-CAG-DIO-NLS-mRuby3-IRES-eGtACR1-ST AAV9 Optogenetics...interest is the Tian lab's pAAV_hSynapsin_psychLight2 (AAV9), which contains a biosensor that detects both serotonin...

...pAAV_hSyn1_nLightG AAV9 Biosensors Patriarchi New viral service pAAV_hSyn1_nLightR AAV9 Biosensors Patriarchi... AAV1, AAV9 Biosensors Li New viral service with multiple serotypes pAAV-hSyn-GRAB_OTmut AAV9 Biosensors...pAAV-hSyn-GRAB_ACh3.0 AAV9 Biosensors Li New viral service pAAV-Ef1a-fDIO-ChrimsonR-tdTomato AAV9 Controls Jensen...serotype pAAV-CAG-2xNLS-tdTomato-WPRE-hGHpolyA AAV9, PHP.eB Controls Feng New viral service, multiple...

...astrocytes (60%) than AAV9 (Ravindra Kumar et al., 2020). AAV9-X1.1 is evolved from AAV9 and transduces GLUT1...capsids are derived from AAV9, their efficacy is generally compared to the AAV9 serotype or an engineered...expression, compared to AAV9, in BALB/cJ mice but is more effective than AAV9 in many other strains, including... efficiency than AAV9 and thus produces lower viral yields. AAV-F, derived from AAV9 using iTransduce,...from variable region VIII of AAV9-X1.1 to that of AAV1. AAV1-X1 reproduces AAV9-X1.1’s brain endothelial ...AAV.CAP-Mac has a lower transduction rate than AAV9 in the liver. AAV9-X1.1 effectively and predominantly transduces...respectively) relative to AAV9 in the pigtail macaque brain slices. Similarly, AAV9-X1.1 outperformed the ...

...first Addgene prep packaged in the AAV9-X1.1 serotype.  In rodents, AAV9-X1.1 enables expression in brain...levels compared to AAV9. You can now target these cells with AAV-CAG-GFP packaged in AAV9-X1.1!  We also ...Recombinases Jonathan Ting New viral prep pAAV-CAG-GFP AAV9-X1.1 Controls Edward Boyden New serotype pAAV-...Loren Looger New serotype pAAV-CAG-FLEx-iSeroSnFR AAV9 Biosensors Lin Tian New viral prep pAAV-hSyn-GRAB-gDA3m...

... CNS. PHP.B, a neurotropic variant of AAV9, is better than AAV9 at gaining access to the CNS of C57BL/...diverse library of AAV9 mutants that had a small randomized peptide loop inserted in the AAV9 capsid. This ...adeno-associated virus (AAV), from reaching their targets. The AAV9 serotype can breach the BBB following injection ...by PHP.B viruses. Creating PHP.B, a neurotropic AAV9 variant PHP.B’s specificity for C57BL/6J mice is...reached the CNS following IV injection. Compared to AAV9, PHP.B has a >40-fold increase in CNS transduction....B required the same receptors that its parental AAV9 relied on for transducing cells: galactose and the...results suggested that PHP.B, unlike its parental AAV9, does not require galactose and AAVR to transduce...

...Name 113050 AAV9, AAVrg pAAV-hSyn-GRAB_DA1h 113049 AAV9 pAAV-hSyn-GRAB_DA1m 123308 AAV9, AAVrg pAAV-hSyn-GRAB_NE1m...Serotype Name 124603 AAV9 pAAV-EF1a-DIO-ChrimsonR-mRuby2-KV2.1-WPRE-SV40 124650 AAV9 pAAV-CamKIIa-C1V1(...readily available to the community. We now offer AAV9 for 2 more constructs from Christopher Harvey’s ...

...axon-GCaMP6s 112005  AAV9 pAAV-hSynapsin1-axon-GCaMP6s-P2A-mRuby3) 112010  AAV9 pAAV-hSynapsin1-FLEx-axon-GCaMP6s...Serotype Name 124651  AAV9  pAAV-CamKIIa-ChrimsonR-mScarlet-KV2.1 124603  AAV9  pAAV-EF1a-DIO-ChrimsonR-mRuby2... 114472  AAV5, AAV8 pAAV-hSyn-mCherry 50459  AAV9, AAVrg pAAV-hSyn-DIO-mCherry 37825 AAV1, 2, 5,...

...available through our in-stock viral prep service.  AAV9 AAV9 has relatively broad tissue tropism and high transduction...cells (Issa et al., 2023). AAV9 packaging plasmids are available at Addgene. AAV9 vectors are not available...CNS AAV1, AAV2, AAV5, AAV8, AAV9, AAVrg Aschauer et al., 2013 Heart AAV9 Bish et al., 2008 Kidney ...AAV8 Laminin receptor (LR)3 AAV receptor2   AAV9 Terminal N-linked galactose3 AAV receptor2 ...targeting the CNS (Issa et al., 2023). Additionally, AAV9 has been shown to transduce liver, skeletal muscle...through our Packaged on Request service, but some AAV9 tools are available as in-stock preparations. AAV...Liver AAV8 Sands, 2011 Lung pUCmini-iCAP-AAV9.452sub.LUNG1 Goertsen et al., 2022 Pancreas AAV6, AAV8...

...AAV4, AAV5, AAV8, AAV9 Heart AAV1, AAV8, AAV9 Kidney AAV2 Liver AAV7, AAV8, AAV9 Lung AAV4, AAV5...AAV5>AAV9>AAV8>AAV1>AAV6>AAV2 Hippocampus AAV9>AAV5>AAV8>AAV1>AAV6>AAV2 Auditory Cortex AAV9>AAV8>...AAV5, AAV6, AAV9 Pancreas AAV8 Photoreceptor Cells AAV2, AAV5, AAV8 RPE (Retinal Pigment Epithelium..., AAV8 Skeletal Muscle AAV1, AAV6, AAV7, AAV8, AAV9 Adapted from https://www.addgene.org/viral-vectors... Oligodendrocytes AAV8 > AAV2 & AAV6 Microglia AAV9 > AAV2 & AAV6 Astrocytes AAV8 > AAV2 & AAV6 ...

...potency of AAV-PHP.eB.    Figure 4: AAV9-X1 and AAV9-X1.1 efficiently transduce brain endothelial...multispecies approach to generate and screen a library of AAV9 variants (Chuapoco et al., 2023). They found the...human neurons, with broader neuronal expression than AAV9. This new capsid will be a valuable tool for investigating...-mer peptide region from variable region VIII of AAV9-X1.1 to that of AAV1. This viral vector has brain...not neutralized by pre-existing antibodies against AAV9-based vectors (and vice versa), enabling repeat ...

...AAV in AAV9 and AAVrg. See our new additions here: Cre vectors pAAV-EF1a-fDIO-Cre (121675-AAV9, 121675...available as 20 ul aliquots in AAV1, AAV2, AAV5, AAV8, AAV9, and AAV Retrograde. You can also request the specific...” pAAV-CamKIIa-ChrimsonR-mScarlet-KV2.1 (124651-AAV9) Recombinase AAV Targeting and manipulating specific...

...AAV5, AAV8, AAV9 Heart AAV1, AAV8, AAV9 Liver AAV7, AAV8, AAV9 Lung AAV4, AAV5, AAV6, AAV9 RPE (Retinal...to be the case for either AAV1 or AAV9. It should be noted that AAV9 was shown to cross the blood brain..., AAV8 Skeletal Muscle AAV1, AAV6, AAV7, AAV8, AAV9 Table 1: Common AAV Serotypes and their target...networks. Kohara et al. 2014 traced neurons with an AAV9 vector expressing a Cre-dependent fluorescent marker... et al. 2017 also provide evidence that AAV1 and AAV9 are capable of synaptic spread. The underlying mechanisms...Chan, C.M. and Kaspar B.K. (2009). Intravascular AAV9 preferentially targets neonatal neurons and adult...

...codon diversified) 37825  AAV8*, AAV9*  pAAV-CAG-GFP 50465  AAV8*, AAV9*  pAAV-hSyn-EGFP *Also coming... 50363  AAV5  AAV phSyn1(S)-DreO-bGHpA 121675  AAV9  pAAV-EF1a-fDIO-Cre (FLP-dependent CRE) 55634 ...

...combined with a Cre-dependent AAV9 tdTomato virus in the mPFC.  The AAV9 is so strong that you can even...

...axon-GCaMP6s-P2A-mKate2 (AAV9) pAAV-hSynapsin1-GCaMP6s-P2A-mKate2 (AAV9) pAAV-hSynapsin1-GCaMP6s-P2A-mRuby3 (AAV9) pAAV-...pAAV-CAG-SomaGCaMP6f2 (AAV9) Plus, additional AAV serotypes of the most recent jGCaMP8 calcium sensors: ...

...PV2723 98929-AAV9 pAAV.hSyn.iGluSnFr.WPRE.SV40 Biosensor Loren Looger AV-9-PV2724 98931-AAV9 pAAV.hSyn.Flex.iGluSnFr.WPRE.SV40...PV2725 98932-AAV9 pAAV.CAG.Flex.iGluSnFr.WPRE.SV40 Biosensor Loren Looger AV-9-PV2816 100835-AAV9 pAAV.CAG.Flex.GCaMP6f.WPRE.SV40...100839-AAV9 pAAV.CAG.Flex.GCaMP6m.WPRE.SV40 Biosensor GENIE, Douglas Kim AV-9-PV2818 100842-AAV9 pAAV.CAG.Flex.GCaMP6s.WPRE.SV40...100833-AAV9 pAAV.Syn.Flex.GCaMP6f.WPRE.SV40 Biosensor GENIE, Douglas Kim AV-9-PV2820 100838-AAV9 pAAV.Syn.Flex.GCaMP6m.WPRE.SV40...100845-AAV9 pAAV.Syn.Flex.GCaMP6s.WPRE.SV40 Biosensor GENIE, Douglas Kim AV-9-PV2822 100837-AAV9 pAAV.Syn.GCaMP6f.WPRE.SV40...PV2823 100841-AAV9 pAAV.Syn.GCaMP6m.WPRE.SV40 Biosensor GENIE, Douglas Kim AV-9-PV2824 100843-AAV9 pAAV.Syn.GCaMP6s.WPRE.SV40...PV2833 100844-AAV9 pAAV.CAG.GCaMP6s.WPRE.SV40 Biosensor GENIE, Douglas Kim AV-9-PV2914 98930-AAV9 pENN.AAV....

...hM4D(Gi) using the CD68 promoter. Bryan Roth 75033-AAV9 pAAV CD68-hM4D(Gi)-mCherry Expression of hM4D(Gi...of the hDlx enhancer element Gordon Fishell 83894-AAV9 pAAV-hDlx-Flex-dTomato-Fishell_7 Cre recombinase-dependent...of the hDlx enhancer element Gordon Fishell 83895-AAV9 pAAV-hDlx-Flex-GFP-Fishell_6 Cre recombinase-dependent...of the hDlx enhancer element Gordon Fishell 83896-AAV9 pAAV-hDlx-GiDREADD-dTomato-Fishell-5 Gi-DREADD (...of the hDlx enhancer element Gordon Fishell 83897-AAV9 pAAV-hDlx-GqDREADD-dTomato-Fishell-4 Gq-DREADD (...of the mDlx enhancer element Gordon Fishell 83898-AAV9 pAAV-mDlx-ChR2-mCherry-Fishell-3 ChR2-mCherry fusion...of the mDlx enhancer element Gordon Fishell 83899-AAV9 pAAV-mDlx-GCaMP6f-Fishell-2 GCaMP6f expression in...

...recommend using one of the natural serotypes such as AAV9 or AAV8. Very recently an engineered AAV5 capsid... of our engineered AAV are presently built on an AAV9 backbone and so will very likely cross-react with...

... AAV8 37825-AAV8.T 20 µL $ 140 Add to Cart AAV9 37825-AAV9.T 20 µL $ 140 Add to Cart AAV Retrograde 37825... AAV8 50465-AAV8.T 20 µL $ 140 Add to Cart AAV9 50465-AAV9.T 20 µL $ 140 Add to Cart AAV Retrograde 50465...for serotype testing: AAV1, AAV2, AAV5, AAV8 and AAV9 Viral...

...Control Boyden AAV9-X1.1 These viral vector preparations were produced with the pUCmini-iCAP-AAV9-X1.1 plasmid....eB PHP.S PHP.V1 MaCPNS1 MaCPNS2 CAP-B10 CAP-B22 AAV9-X1.1 As part of our Viral Vector Packaging Service... for LY6A-permissive mouse strains). AAV-PHP.eC, AAV9-X1.1 and AAV1-X1 do not display strain-specific ...plasmid (Addgene #196836) . Browse Available AAV9-X1.1 ID Name Promoter Description Category PI 37825 pAAV-CAG-GFP...2022 Pubmed 34887588 (Link opens in a new window) AAV9-X1.1: Chen et al., 2023 Pubmed 37291094 (Link opens...AAV.MaCPNS2 Cell type-biased: Neurons - AAV.CAP-Mac, AAV9-X1.1 For marmosets: Broad tropism - AAV.CAP-B22 ...type-biased: Neurons - AAV.CAP-Mac Brain vascular cells - AAV9-X1.1, AAV1-X1 For mice: Broad tropism - AAV-PHP....