962 results

Prime editing is a search-and-replace CRISPR editing method that offers versatility and precision in genome editing. We cover common prime editing tools.

Aug. 11, 2026, 1:15 p.m.

Learn about the latest statistics on CRISPR plasmid deposits and distributions and how this reflects the broader CRISPR community.

Aug. 6, 2026, 7 p.m.

Addgene co-founder Melina Fan is transitioning to our Chief Scientific Advisor. We reflect on our history, how science has changed, and what comes next.

Aug. 4, 2026, 1:15 p.m.

Learn what non-model organisms are, why scientists use them, and what they can teach us.

July 21, 2026, 1:15 p.m.

Learn how to navigate the PhD job market, from choosing between academia and industry to translating your skills and positioning yourself for the right role.

July 7, 2026, 1:30 p.m.

The REPROcode collection includes 408 barcoded lentiviral vectors carrying immune-specific transcription factors, allowing transdifferentiation screens.

June 23, 2026, 1:15 p.m.

High schoolers invented a new diagnostic for Lyme disease. In the process, they also created a tool for jointly designing RPA primers and Cas12a sgRNAs.

May 12, 2026, 1:15 p.m.

Learn about new tools in Addgene's collection, including new biosensors for neuroscience research, plasmids for a common lab enzyme, and more!

May 5, 2026, 1:15 p.m.

Addgene has a new brand identity! This post describes the design decisions that went into our new logo, style, introductory video, and our mascot, Blugene.

April 28, 2026, 1:15 p.m.

Synthetic origins of replication, or ORIs, from the Chappell Lab have improved plasmid compatibility and copy number control compared to natural ORIs.

April 14, 2026, 1:14 p.m.

This post, written by the creator of the CRISPRecise kit, explains how to use it to minimize off-target effects in CRISPR genome editing.

March 31, 2026, 1:15 p.m.

This post discusses takeaways from, and tools presented at, the Deaminet 2026 conference, focusing on base editors, prime editors, and translational work.

March 10, 2026, 1:14 p.m.

This post describes the development of sentinel plants, which change color to alert humans when they detect certain molecules in their environment.

March 3, 2026, 2:14 p.m.

Learn about hot new tools in our collection!

Feb. 17, 2026, 2:15 p.m.

Learn about what's coming for Addgene in 2026

Feb. 5, 2026, 4:15 p.m.

This post discusses the applications, advantages, and caveats to using hybrid guide RNAs, in which DNA bases are substituted for RNA bases.

Jan. 27, 2026, 2:14 p.m.

This post highlights some of the tools Addgene makes available to industry scientists.

Jan. 13, 2026, 2:15 p.m.

This post describes applications of pooled libraries, briefly explains several approaches, and highlights the most popular pooled libraries at Addgene.

Nov. 19, 2025, 2:15 p.m.

Learn about new tools in Addgene's collection!

Nov. 11, 2025, 2:14 p.m.

Learn about click biology and how you can use it to advance your experiments and explore biological phenomenon.

Oct. 21, 2025, 1:15 p.m.

Learn more about NanoBiT technology and explore examples of HiBiT-tagged fusion proteins in action.

Oct. 2, 2025, 1:15 p.m.

Baby KJ was treated for his devastating genetic disorder with CRISPR base editing. This post describes the prior advances that made his cure possible.

Sept. 16, 2025, 1:15 p.m.

Learn about the best-in-class collection of AAV enhancers developed by the Allen Institute for Brain Science!

Sept. 9, 2025, 1:15 p.m.

Check out the latest Hot Plasmids, viral vectors, and antibodies in the Addgene repository!

Aug. 28, 2025, 1:15 p.m.

Learn about OCaMP, a new orange genetically encoded calcium indicator .

Aug. 19, 2025, 1:15 p.m.

Learn about antibody engineering, including what it is and why we like it. Deep dive into antibody directed evolution techniques, and learn about Addgene's partnership with the Institute for Protein Innovation (IPI).

Aug. 5, 2025, 1:15 p.m.

Learn about TnpB, a small genome editor with a function similar to CRISPR systems!

July 29, 2025, 1:15 p.m.

Learn more about luciferases, a class of enzymes used in bioluminescence, and how they are commonly used in reporter plasmids.

July 22, 2025, 1:15 p.m.

Learn about what sequencing technologies the quality control team at Addgene uses to maintain a high standard of plasmid and viral vector quality.

July 15, 2025, 1:15 p.m.

Learn about the best tips and tricks for modular cloning (MoClo) of plasmids!

July 8, 2025, 1:15 p.m.

Learn about evaluating DNA quality with Spectophotometry using a Nanodrop

July 1, 2025, 1:15 p.m.

We're updating our Hold for Publication policy. Read about how these changes will help streamline our workflows and get your plasmids online faster!

June 24, 2025, 1:15 p.m.

Learn about RNA interference and how you can use shRNA plasmids to knockdown gene expression!

June 17, 2025, 1:15 p.m.

This post describes evoCAST, a new CRISPR-associated transposase tools optimized for genetic editing in human cells.

June 10, 2025, 1:15 p.m.

Check out the latest Hot Plasmids, viral vectors, and antibodies in the Addgene repository!

June 3, 2025, 1:15 p.m.

Learn how to select the plasmid purification kit that best suits your needs!

May 27, 2025, 1:15 p.m.

This post describes the design of shuttle vectors, which are designed for replication, selection, and expression in more than one host species.

May 20, 2025, 1:15 p.m.

This post describes the biology and use of integrase-deficient lentiviral vectors in comparison to standard lentiviral vectors.

May 13, 2025, 1:15 p.m.

Learn about Addgene's QC process and how and why we maintain a high standard of sequence accuracy across our plasmid collection.

May 6, 2025, 1:15 p.m.

Addgene adds new ready-to-use viral vectors to our service every month. Read all about the latest additions here!

April 29, 2025, 1:30 p.m.