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This blog series showcases some of the new CRISPR tools we have at Addgene each quarter.

Dec. 18, 2018, 1:17 p.m.

Learn about the many ways you can deliver reprogramming factors to generate induced pluripotent stem cells (IPSCs).

April 17, 2018, 1:37 p.m.

Exercised or endurance-induced expression of PGC-1a1 in skeletal muscle protects the brain from depression in mice.

Nov. 25, 2014, 4:02 p.m.

Review of off-target effects in CRISPR experiments. Topics covered include: measuring, preventing, and controlling for off-target events.

Feb. 8, 2024, 2:15 p.m.

Introduction to immunofluorescence and how you can use it to illuminate your research.

Nov. 16, 2021, 2:15 p.m.

Since several sets of near-infrared fluorescent proteins (NIR FPs) and biosensors have been created recently, we've added a quick guide to help you choose the best probe for your research needs.

Oct. 5, 2021, 1:15 p.m.

Model organisms have genetic and developmental characteristics that make them easy to study. Examples include E. coli, rat, frog, axolotl, and Arabidopsis.

Sept. 29, 2020, 1:15 p.m.

Read on for a sampling of some of the exciting new plasmid technologies that have come through our doors in 2015.

Dec. 23, 2015, 3:30 p.m.

Learn about hot new tools in our collection!

Feb. 17, 2026, 2:15 p.m.

Check out the latest Hot Plasmids, viral vectors, and antibodies in the Addgene repository!

June 3, 2025, 1:15 p.m.

Antibody validation shows that your antibody is targeting exactly what it is supposed to. This post walks through 5 validation strategies.

March 24, 2022, 1:15 p.m.

An overview of the western blotting process from separating proteins by size, transfer, staining, and visualizing.

March 8, 2021, 2:41 p.m.

Epigenetic modifications are an additional layer of control over gene expression. Targeted epigenetic modification is possible using CRISPR tools from Addgene!

June 24, 2020, 5:45 p.m.

Learn about a useful technique to screen phage genomes for host binding proteins and discover new research avenues.

Sept. 29, 2016, 2:30 p.m.

Learn the basics behind generating generating mouse models using CRISPR/Cas9.

July 12, 2016, 2:30 p.m.

The pCri plasmids available through Addgene allow researchers to multiplex the protein purification process saving time and frustration.

June 19, 2015, 3:08 p.m.

Learn how you can use acoustic reporter genes for in vivo imaging experiments. These are good alternatives to fluorescence reporters.

June 19, 2018, 1:38 p.m.

The Addgene Blue Flame Awards celebrate depositors with highly requested plasmids. Learn more about the awards here.

Nov. 14, 2016, 3:30 p.m.

This blog post explores how commonly used GFP variants can undergo Green-Red photoconversion.

Aug. 4, 2015, 2:30 p.m.

Overview of recombinases that can be used as a Cre-alternative for site-specific recombination in Drosophila.

May 12, 2015, 1:32 p.m.