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An overview of gRNA modifications available to CRISPR users and some of the advantages of using synthetically modified guides in your experiments.

Oct. 20, 2022, 1:15 p.m.

What are we asking of our audience when we tell them about our science? Cognitive load explains how your learners have to work too.

June 16, 2022, 1:15 p.m.

Learn about the latest CRISPR plasmids deposited at Addgene, including a miniature CRISPR-Cas systems, SEND plasmids, and prime editing improvements

Nov. 18, 2021, 2:15 p.m.

New channelrhodropsins, called ChRgers, avoid intracranial injections and fiber-optic cable implantation for in vivo optogenetics experiments.

Nov. 3, 2020, 2:15 p.m.

Learn how you can use photoswitchable kinases to control signaling pathways with light!

July 25, 2017, 1:20 p.m.

Check out how you can use digital PCR to validate your CRISPR genome edits.

March 30, 2017, 2:30 p.m.

Future of Research Executive Director, Gary McDowell, explains how evolving wage regulations are impacting universities' decisions to change postdoc salaries.

Jan. 11, 2017, 3:30 p.m.

The Future of Research Symposium Boston 2015 aims to develop solutions to problems in academic research. Learn how you can get involved .

Oct. 20, 2015, 2:30 p.m.

Tips for writing your scientific manuscript, including how to search for and organize papers.

May 5, 2015, 3:54 p.m.

Learn about Addgene's QC process and how and why we maintain a high standard of sequence accuracy across our plasmid collection.

May 6, 2025, 1:15 p.m.

There are a few different types of Fab fragments to consider when you need a smaller affinity reagent than antibodies. Learn about them here!

Sept. 5, 2024, 1:15 p.m.

A review of alternative PAM and PAM-flexible Cas enzymes.

March 7, 2024, 2:39 p.m.

An easy demethylation protocol uses CRISPR-based dCas9-directed DNA avoids the use of Tet

Dec. 14, 2021, 2:15 p.m.

ELISA are used to quantitatively detect protein concentrations in experimental samples. Learn about different types of ELISA and when to choose each method.

Aug. 24, 2021, 1:15 p.m.

Find the latest plasmids and viral vectors to available at Addgene in the October 2020 hot plasmids blog post!

Oct. 13, 2020, 1:15 p.m.

Nanoblades are a CRISPR delivery tool. These Nanoblades are engineered MLV-like particles loaded with Cas9-gRNA ribonucleoproteins.

Sept. 26, 2019, 12:50 p.m.

Gamma-retroviral vectors and lentiviral vectors can be used in a wide variety of experiments including those involving genome engineering, RNAi, and inducible gene expression. In this post, learn about some of the most popular viral vectors available from Addgene and their uses.

July 24, 2018, 12:51 p.m.

Learn how you can use planarian plasmids from the Sánchez lab to teach developmental biology techniques to new molecular biologists.

May 24, 2018, 1:20 p.m.

Learn all about new optogentics tools, caffeine degradation, biosensors, and new fluorescent proteins.

May 15, 2018, 12:43 p.m.

Learn how you can use split-BioID to study protein-protein interactions and build a better understand of your protein's interactome.

May 1, 2018, 1:57 p.m.