Click Biology: How to Click and Play to Explore Biology
Type
Blog Post
Published
Oct. 21, 2025, 1:15 p.m.
...split intein; N-terminal CLm and C-terminal Aes
gp41-1
Split inteins
A small, fast split intein
SpyTag003...the best performance in the most contexts (Figure 1). Together the features with optimal biological performance...described as Click Biology (Howarth, 2025).
Figure 1: Modular assembly tools, alongside criteria for Click...tools can be found in Addgene's repository (Table 1).
Figure 2: Adding function to My Favorite ...coupling. Created with BioRender.com.
Table 1: A handful of Click Biology tools available at Addgene...