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...hands on PGC-1a for studies in your own lab, you’ve come to the right place. Get started with PGC-1 plasmids....2014.09.012. PMID: 25295784 Related Materials: PGC-1a Plasmids      ...It’s well known that exercise can help fight stress and depression, and now researchers have reported...findings in a recent issue of Cell demonstrate how PGC-1a1, a transcriptional coactivator induced in skeletal...Mice that are genetically modified to produce extra PGC-1a1 only in their skeletal muscle show resistance...interest in sweets. Further examination of the mck-PGC-1a1 mice found it wasn’t that they were simply immune...brains were protected. Effects of Activation of the PGC-1a1 Pathway Gene expression analysis of the animals...