Rett Syndrome
Type
Collection
...Publication PI Mecp2 NLucTom Knock-in of NLuc-tdTomato at endogenous MECP2 locus Castaneus MECP2-NLuc-tdTomato...) OMIM MECP2 - MECP2 curated literature information (Link opens in a new window) UniProt MECP2 - MECP2... in the gene methyl-CpG binding protein 2 ( MECP2 ). MECP2 Rett syndrome is an X-linked disorder caused...half of cells expressing wild-type MECP2 and half expressing mutant MECP2 . Skewing of these X inactivation...major function of MECP2 is to regulate gene expression either locally or globally. The MECP2 protein contains...include MECP2 null alleles or common mutations that recapitulate Rett syndrome in humans. MECP2 knockout...Plasmids MECP2 Plasmids The table below highlights plasmids that express or target the MECP2 gene. Use...