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Plasmid
14886:
IgK-IFN-luc
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Addgene has sequenced a portion of this plasmid for verification. Click here for the sequencing result. CARD11 mediates factor-specific activation of NF-kappaB by the T cell receptor complex. Pomerantz et al (EMBO J. 2002 Oct 1. 21(19):5184-94. PubMed) Please acknowledge the principal investigator and cite this article if you use this plasmid in a publication. Also, please include the text "Addgene plasmid 14886" in your Materials and Methods section. |
Contains two copies of the immunoglobulin kappa light chain kappa-B site (5'-GGGGACTTTCC-3') upstream of the interferon-beta minimal promoter (–55 to +19) (Fujita et al., 1987) driving luciferase expression.