AAV.TBG.PI.Cre.rBG Citations (53)
Originally described in: AAV plasmidsUnpublished
Articles Citing AAV.TBG.PI.Cre.rBG
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| Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis. Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. PubMed |
| Collapse of the hepatic gene regulatory network in the absence of FoxA factors. Reizel Y, Morgan A, Gao L, Lan Y, Manduchi E, Waite EL, Wang AW, Wells A, Kaestner KH. Genes Dev. 2020 Aug 1;34(15-16):1039-1050. doi: 10.1101/gad.337691.120. Epub 2020 Jun 19. PubMed |
| Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling. Weng Y, Lieberthal TJ, Zhou VX, Lopez-Ichikawa M, Armas-Phan M, Bond TK, Yoshida MC, Choi WT, Chang TT. JCI Insight. 2020 Oct 15;5(20). pii: 141217. doi: 10.1172/jci.insight.141217. PubMed |
| Cell type-selective secretome profiling in vivo. Wei W, Riley NM, Yang AC, Kim JT, Terrell SM, Li VL, Garcia-Contreras M, Bertozzi CR, Long JZ. Nat Chem Biol. 2021 Mar;17(3):326-334. doi: 10.1038/s41589-020-00698-y. Epub 2020 Nov 16. PubMed |
| A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21. Han MS, Perry RJ, Camporez JP, Scherer PE, Shulman GI, Gao G, Davis RJ. Genes Dev. 2021 Jan 1;35(1-2):133-146. doi: 10.1101/gad.344556.120. Epub 2020 Dec 17. PubMed |
| Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis. Anastasia I, Ilacqua N, Raimondi A, Lemieux P, Ghandehari-Alavijeh R, Faure G, Mekhedov SL, Williams KJ, Caicci F, Valle G, Giacomello M, Quiroga AD, Lehner R, Miksis MJ, Toth K, de Aguiar Vallim TQ, Koonin EV, Scorrano L, Pellegrini L. Cell Rep. 2021 Mar 16;34(11):108873. doi: 10.1016/j.celrep.2021.108873. PubMed |
| Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, Saito Y, Savage T, Wells RG, Mack M, Zender L, Arpaia N, Remotti HE, Rabadan R, Sims P, Leblond AL, Weber A, Riener MO, Stockwell BR, Gaublomme J, Llovet JM, Kalluri R, Michalopoulos GK, Seki E, Sia D, Chen X, Califano A, Schwabe RF. Cancer Cell. 2021 Jun 14;39(6):866-882.e11. doi: 10.1016/j.ccell.2021.03.012. Epub 2021 Apr 29. PubMed |
| Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice. Dalton GD, Oh SH, Tang L, Zhang S, Brown AL, Varadharajan V, Baleanu-Gogonea C, Gogonea V, Pathak P, Brown JM, Diehl AM. iScience. 2021 Sep 4;24(9):103089. doi: 10.1016/j.isci.2021.103089. eCollection 2021 Sep 24. PubMed |
| p53-mediated redox control promotes liver regeneration and maintains liver function in response to CCl4. Humpton TJ, Hall H, Kiourtis C, Nixon C, Clark W, Hedley A, Shaw R, Bird TG, Blyth K, Vousden KH. Cell Death Differ. 2022 Mar;29(3):514-526. doi: 10.1038/s41418-021-00871-3. Epub 2021 Oct 9. PubMed |
| A three-organelle complex made by wrappER contacts with peroxisomes and mitochondria responds to liver lipid flux changes. Ilacqua N, Anastasia I, Raimondi A, Lemieux P, de Aguiar Vallim TQ, Toth K, Koonin EV, Pellegrini L. J Cell Sci. 2022 Mar 1;135(5):jcs259091. doi: 10.1242/jcs.259091. Epub 2021 Nov 2. PubMed |
| Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage. Praestholm SM, Correia CM, Goitea VE, Siersbaek MS, Jorgensen M, Havelund JF, Pedersen TA, Faergeman NJ, Grontved L. Cell Rep. 2021 Nov 2;37(5):109938. doi: 10.1016/j.celrep.2021.109938. PubMed |
| Single-cell transcriptomics reveals opposing roles of Shp2 in Myc-driven liver tumor cells and microenvironment. Chen WS, Liang Y, Zong M, Liu JJ, Kaneko K, Hanley KL, Zhang K, Feng GS. Cell Rep. 2021 Nov 9;37(6):109974. doi: 10.1016/j.celrep.2021.109974. PubMed |
| RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state. Belenguer G, Mastrogiovanni G, Pacini C, Hall Z, Dowbaj AM, Arnes-Benito R, Sljukic A, Prior N, Kakava S, Bradshaw CR, Davies S, Vacca M, Saeb-Parsy K, Koo BK, Huch M. Nat Commun. 2022 Jan 17;13(1):334. doi: 10.1038/s41467-021-27923-z. PubMed |
| FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit. Flippo KH, Trammell SAJ, Gillum MP, Aklan I, Perez MB, Yavuz Y, Smith NK, Jensen-Cody SO, Zhou B, Claflin KE, Beierschmitt A, Fink-Jensen A, Knop FK, Palmour RM, Grueter BA, Atasoy D, Potthoff MJ. Cell Metab. 2022 Feb 1;34(2):317-328.e6. doi: 10.1016/j.cmet.2021.12.024. PubMed |
| Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure. Katsumura S, Siddiqui N, Goldsmith MR, Cheah JH, Fujikawa T, Minegishi G, Yamagata A, Yabuki Y, Kobayashi K, Shirouzu M, Inagaki T, Huang TH, Musi N, Topisirovic I, Larsson O, Morita M. Cell Metab. 2022 Apr 5;34(4):564-580.e8. doi: 10.1016/j.cmet.2022.03.005. PubMed |
| Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis. Filliol A, Saito Y, Nair A, Dapito DH, Yu LX, Ravichandra A, Bhattacharjee S, Affo S, Fujiwara N, Su H, Sun Q, Savage TM, Wilson-Kanamori JR, Caviglia JM, Chin L, Chen D, Wang X, Caruso S, Kang JK, Amin AD, Wallace S, Dobie R, Yin D, Rodriguez-Fiallos OM, Yin C, Mehal A, Izar B, Friedman RA, Wells RG, Pajvani UB, Hoshida Y, Remotti HE, Arpaia N, Zucman-Rossi J, Karin M, Henderson NC, Tabas I, Schwabe RF. Nature. 2022 Oct;610(7931):356-365. doi: 10.1038/s41586-022-05289-6. Epub 2022 Oct 5. PubMed |
| MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities. Sequera C, Grattarola M, Holczbauer A, Dono R, Pizzimenti S, Barrera G, Wangensteen KJ, Maina F. Cell Death Dis. 2022 Nov 24;13(11):994. doi: 10.1038/s41419-022-05411-6. PubMed |
| Inter-organ insulin-leptin signal crosstalk from the liver enhances survival during food shortages. Takahashi K, Yamada T, Hosaka S, Kaneko K, Asai Y, Munakata Y, Seike J, Horiuchi T, Kodama S, Izumi T, Sawada S, Hoshikawa K, Inoue J, Masamune A, Ueno Y, Imai J, Katagiri H. Cell Rep. 2023 May 30;42(5):112415. doi: 10.1016/j.celrep.2023.112415. Epub 2023 Apr 27. PubMed |
Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion.
Minami Y, Hoshino A, Higuchi Y, Hamaguchi M, Kaneko Y, Kirita Y, Taminishi S, Nishiji T, Taruno A, Fukui M, Arany Z, Matoba S.
Nat Commun. 2023 Jul 13;14(1):4084. doi: 10.1038/s41467-023-39404-6.
PubMed
Associated Plasmids |
| Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice. Yu L, Xu L, Chu H, Peng J, Sacharidou A, Hsieh HH, Weinstock A, Khan S, Ma L, Duran JGB, McDonald J, Nelson ER, Park S, McDonnell DP, Moore KJ, Huang LJ, Fisher EA, Mineo C, Huang L, Shaul PW. Nat Commun. 2023 Jul 25;14(1):4101. doi: 10.1038/s41467-023-39586-z. PubMed |
| Autophagy modulates the stability of Wee1 and cell cycle G2/M transition. Han B, Chen Y, Song C, Chen Y, Chen Y, Ferguson D, Yang Y, He A. Biochem Biophys Res Commun. 2023 Oct 15;677:63-69. doi: 10.1016/j.bbrc.2023.08.010. Epub 2023 Aug 4. PubMed |
| Adenosine A2A receptor is a tumor suppressor of NASH-associated hepatocellular carcinoma. Allard B, Jacoberger-Foissac C, Cousineau I, Bareche Y, Buisseret L, Chrobak P, Allard D, Pommey S, Ah-Pine F, Duquenne S, Picard F, Stagg J. Cell Rep Med. 2023 Sep 19;4(9):101188. doi: 10.1016/j.xcrm.2023.101188. PubMed |
| Hepatic sialic acid synthesis modulates glucose homeostasis in both liver and skeletal muscle. Peng J, Yu L, Huang L, Paschoal VA, Chu H, de Souza CO, Varre JV, Oh DY, Kohler JJ, Xiao X, Xu L, Holland WL, Shaul PW, Mineo C. Mol Metab. 2023 Dec;78:101812. doi: 10.1016/j.molmet.2023.101812. Epub 2023 Sep 28. PubMed |
| Periportal hepatocyte proliferation at midgestation governs maternal glucose homeostasis in mice. Kozuki S, Kabata M, Sakurai S, Iwaisako K, Nishimura T, Toi M, Yamamoto T, Toyoshima F. Commun Biol. 2023 Dec 4;6(1):1226. doi: 10.1038/s42003-023-05614-3. PubMed |
| Chemically induced revitalization of damaged hepatocytes for regenerative liver repair. Lin P, Bai Y, Nian X, Chi J, Chen T, Zhang J, Zhang W, Zhou B, Liu Y, Zhao Y. iScience. 2023 Nov 23;26(12):108532. doi: 10.1016/j.isci.2023.108532. eCollection 2023 Dec 15. PubMed |
| Fatty liver disease protective MTARC1 p.A165T variant reduces the protein stability of MTARC1. Wu M, Tie M, Hu L, Yang Y, Chen Y, Ferguson D, Chen Y, He A. Biochem Biophys Res Commun. 2024 Apr 2;702:149655. doi: 10.1016/j.bbrc.2024.149655. Epub 2024 Feb 7. PubMed |
| Modifications of the GH Axis Reveal Unique Sexually Dimorphic Liver Signatures for Lcn13, Asns, Hamp2, Hao2, and Pgc1a. Brie B, Sarmento-Cabral A, Pascual F, Cordoba-Chacon J, Kineman RD, Becu-Villalobos D. J Endocr Soc. 2024 Jan 31;8(3):bvae015. doi: 10.1210/jendso/bvae015. eCollection 2024 Jan 16. PubMed |
| Multi-scale in vivo imaging of tumour development using a germline conditional triple-reporter system. Dzien P, Raffo Iraolagoitia X, May S, Stevenson D, McGarry L, Soloviev D, Brown G, Nixon C, Kapeni C, De La Roche M, Blyth K, Lyons S, Bird T, Strathdee D, Fruhwirth G, Carlin L, Lewis D. Res Sq [Preprint]. 2024 Apr 3:rs.3.rs-4196140. doi: 10.21203/rs.3.rs-4196140/v1. PubMed |
| Multimodal decoding of human liver regeneration. Matchett KP, Wilson-Kanamori JR, Portman JR, Kapourani CA, Fercoq F, May S, Zajdel E, Beltran M, Sutherland EF, Mackey JBG, Brice M, Wilson GC, Wallace SJ, Kitto L, Younger NT, Dobie R, Mole DJ, Oniscu GC, Wigmore SJ, Ramachandran P, Vallejos CA, Carragher NO, Saeidinejad MM, Quaglia A, Jalan R, Simpson KJ, Kendall TJ, Rule JA, Lee WM, Hoare M, Weston CJ, Marioni JC, Teichmann SA, Bird TG, Carlin LM, Henderson NC. Nature. 2024 Jun;630(8015):158-165. doi: 10.1038/s41586-024-07376-2. Epub 2024 May 1. PubMed |
| PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein. Johnson SM, Bao H, McMahon CE, Chen Y, Burr SD, Anderson AM, Madeyski-Bengtson K, Linden D, Han X, Liu J. Nat Commun. 2024 Jun 6;15(1):4847. doi: 10.1038/s41467-024-49224-x. PubMed |
| NCLX controls hepatic mitochondrial Ca(2+) extrusion and couples hormone-mediated mitochondrial Ca(2+) oscillations with gluconeogenesis. Taha M, Assali EA, Ben-Kasus Nissim T, Stutzmann GE, Shirihai OS, Hershfinkel M, Sekler I. Mol Metab. 2024 Sep;87:101982. doi: 10.1016/j.molmet.2024.101982. Epub 2024 Jul 1. PubMed |
| Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression. Asantewaa G, Tuttle ET, Ward NP, Kang YP, Kim Y, Kavanagh ME, Girnius N, Chen Y, Rodriguez K, Hecht F, Zocchi M, Smorodintsev-Schiller L, Scales TQ, Taylor K, Alimohammadi F, Duncan RP, Sechrist ZR, Agostini-Vulaj D, Schafer XL, Chang H, Smith ZR, O'Connor TN, Whelan S, Selfors LM, Crowdis J, Gray GK, Bronson RT, Brenner D, Rufini A, Dirksen RT, Hezel AF, Huber AR, Munger J, Cravatt BF, Vasiliou V, Cole CL, DeNicola GM, Harris IS. Nat Commun. 2024 Jul 21;15(1):6152. doi: 10.1038/s41467-024-50454-2. PubMed |
| Hepatocyte-specific Epidermal Growth Factor Receptor Deletion Promotes Fibrosis but has no Effect on Steatosis in Fast-food Diet Model of Metabolic Dysfunction-associated Steatotic Liver Disease. Bano S, Copeland MA, Stoops JW, Orr A, Jain S, Paranjpe S, Mooli RGR, Ramakrishnan SK, Locker J, Mars WM, Michalopoulos GK, Bhushan B. Cell Mol Gastroenterol Hepatol. 2024;18(4):101380. doi: 10.1016/j.jcmgh.2024.101380. Epub 2024 Jul 20. PubMed |
| A hierarchical hepatic de novo lipogenesis substrate supply network utilizing pyruvate, acetate, and ketones. Rauckhorst AJ, Sheldon RD, Pape DJ, Ahmed A, Falls-Hubert KC, Merrill RA, Brown RF, Deshmukh K, Vallim TA, Deja S, Burgess SC, Taylor EB. Cell Metab. 2025 Jan 7;37(1):255-273.e6. doi: 10.1016/j.cmet.2024.10.013. Epub 2024 Oct 28. PubMed |
| A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function. Saunders RA, Allen WE, Pan X, Sandhu J, Lu J, Lau TK, Smolyar K, Sullivan ZA, Dulac C, Weissman JS, Zhuang X. bioRxiv [Preprint]. 2025 Feb 17:2024.11.18.624217. doi: 10.1101/2024.11.18.624217. PubMed |
| FBP1 controls liver cancer evolution from senescent MASH hepatocytes. Gu L, Zhu Y, Nandi SP, Lee M, Watari K, Bareng B, Ohira M, Liu Y, Sakane S, Carlessi R, Sauceda C, Dhar D, Ganguly S, Hosseini M, Teneche MG, Adams PD, Gonzalez DJ, Kisseleva T, Tirnitz-Parker JEE, Simon MC, Alexandrov LB, Karin M. Nature. 2025 Jan;637(8045):461-469. doi: 10.1038/s41586-024-08317-9. Epub 2025 Jan 1. PubMed |
| In Vivo CRISPR Activation Screening Reveals Chromosome 1q Genes VPS72, GBA1, and MRPL9 Drive Hepatocellular Carcinoma. Vazquez Salgado AM, Cai C, Lee M 2nd, Yin D, Chrystostome ML, Gefre AF, He S, Kieckhaefer JE, Wangensteen KJ. Cell Mol Gastroenterol Hepatol. 2025;19(5):101460. doi: 10.1016/j.jcmgh.2025.101460. Epub 2025 Jan 4. PubMed |
| Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury. Herrera JM, Weng Y, Lieberthal TJ, Paoletti M, Chang TT. Hepatol Commun. 2025 Jan 29;9(2):e0636. doi: 10.1097/HC9.0000000000000636. eCollection 2025 Feb 1. PubMed |
| An Nrf2-NF-kappaB Crosstalk Controls Hepatocyte Proliferation in the Normal and Injured Liver. Kuklin A, Slabber CF, Tortola L, Kwan CL, Liebisch G, Kondylis V, Mair F, Kopf M, Weber A, Werner S. Cell Mol Gastroenterol Hepatol. 2025;19(7):101480. doi: 10.1016/j.jcmgh.2025.101480. Epub 2025 Feb 17. PubMed |
| Human-correlated genetic models identify precision therapy for liver cancer. Muller M, May S, Hall H, Kendall TJ, McGarry L, Blukacz L, Nuciforo S, Georgakopoulou A, Jamieson T, Phinichkusolchit N, Dhayade S, Suzuki T, Huguet-Pradell J, Powley IR, Officer-Jones L, Pennie RL, Esteban-Fabro R, Gris-Oliver A, Pinyol R, Skalka GL, Leslie J, Hoare M, Sprangers J, Malviya G, Mackintosh A, Johnson E, McCain M, Halpin J, Kiourtis C, Nixon C, Clark G, Clark W, Shaw R, Hedley A, Drake TM, Tan EH, Neilson M, Murphy DJ, Lewis DY, Reeves HL, Le Quesne J, Mann DA, Carlin LM, Blyth K, Llovet JM, Heim MH, Sansom OJ, Miller CJ, Bird TG. Nature. 2025 Mar;639(8055):754-764. doi: 10.1038/s41586-025-08585-z. Epub 2025 Feb 19. PubMed |
| Hepatic stellate cells control liver zonation, size and functions via R-spondin 3. Sugimoto A, Saito Y, Wang G, Sun Q, Yin C, Lee KH, Geng Y, Rajbhandari P, Hernandez C, Steffani M, Qie J, Savage T, Goyal DM, Ray KC, Neelakantan TV, Yin D, Melms J, Lehrich BM, Yasaka TM, Liu S, Oertel M, Lan T, Guillot A, Peiseler M, Filliol A, Kanzaki H, Fujiwara N, Ravi S, Izar B, Brosch M, Hampe J, Remotti H, Argemi J, Sun Z, Kendall TJ, Hoshida Y, Tacke F, Fallowfield JA, Blockley-Powell SK, Haeusler RA, Steinman JB, Pajvani UB, Monga SP, Bataller R, Masoodi M, Arpaia N, Lee YA, Stockwell BR, Augustin HG, Schwabe RF. Nature. 2025 Apr;640(8059):752-761. doi: 10.1038/s41586-025-08677-w. Epub 2025 Mar 12. PubMed |
| Disrupting bile acid metabolism by suppressing Fxr causes hepatocellular carcinoma induced by YAP activation. Liu Y, Zhu J, Jin Y, Sun Z, Wu X, Zhou H, Yang Y. Nat Commun. 2025 Apr 15;16(1):3583. doi: 10.1038/s41467-025-58809-z. PubMed |
| METTL14-Induced M(6)A Methylation Increases G6pc Biosynthesis, Hepatic Glucose Production and Metabolic Disorders in Obesity. Zheng Q, Zhong X, Kang Q, Zhang Z, Ren D, Liu Y, Rui L. Adv Sci (Weinh). 2025 Jun;12(22):e2417355. doi: 10.1002/advs.202417355. Epub 2025 Apr 25. PubMed |
| HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury. Yuan WC, Earl AS, Ma S, Alcedo K, Russell JO, Duarte FM, Chu YT, Chang PC, Chen HY, Chi HH, Zhu Q, Rodriguez-Fraticelli AE, Patel SH, Lee YR, Buenrostro JD, Camargo FD. Cell Stem Cell. 2025 Jun 5;32(6):990-1005.e8. doi: 10.1016/j.stem.2025.04.010. Epub 2025 May 21. PubMed |
| Loss of hepatic autophagy induces alpha-cell proliferation through impaired glutamine-dependent gluconeogenesis. Velasco-Silva JN, Wilkerson JL, Ramos D, Low HK, Bowman F, Evason KJ, Boudina S, Holland WL, Ducker GS. Physiol Rep. 2025 May;13(10):e70381. doi: 10.14814/phy2.70381. PubMed |
| Ethanol induction of FGF21 in the liver is dependent on histone acetylation and ligand activation of ChREBP by glycerol-3-phosphate. Cheong MC, Mackowiak B, Kim HB, Hernandez G, Nandu T, Vale K, Zhang Y, Zacharias LG, Mathews TP, Gao B, Kraus WL, Kliewer SA, Mangelsdorf DJ. Proc Natl Acad Sci U S A. 2025 Jun 3;122(22):e2505263122. doi: 10.1073/pnas.2505263122. Epub 2025 May 29. PubMed |
| Hepatic Nuclear Factor Erythroid 2 Related Factor 1 Activity Promotes Host Defense in Endotoxemia and Bacterial Sepsis. Trites MJ, Li L, Njoku U, Akl MG, Hydomako A, Widenmaier SB. Cell Mol Gastroenterol Hepatol. 2025;19(9):101550. doi: 10.1016/j.jcmgh.2025.101550. Epub 2025 May 29. PubMed |
| Perturb-Multimodal: A platform for pooled genetic screens with imaging and sequencing in intact mammalian tissue. Saunders RA, Allen WE, Pan X, Sandhu J, Lu J, Lau TK, Smolyar K, Sullivan ZA, Dulac C, Weissman JS, Zhuang X. Cell. 2025 Aug 21;188(17):4790-4809.e22. doi: 10.1016/j.cell.2025.05.022. Epub 2025 Jun 12. PubMed |
| Liver CYP4A autophagic lysosomal degradation: A major role for the autophagic receptor SQSTM1/p62 through an uncommon target interaction site. He L, Kwon D, Trnka MJ, Liu Y, Yang J, Li KH, Totah RA, Johnson EF, Burlingame AL, Correia MA. Mol Pharmacol. 2025 Sep;107(9):100061. doi: 10.1016/j.molpha.2025.100061. Epub 2025 Jul 11. PubMed |
| SALL4 Is Required for YAP1-Dependent Malignant and Regenerative Hepatocyte-to-Cholangiocyte Reprogramming. Kim M, Park Y, Covitz R, Kwon J, Liu JJ, Liu S, Ko S. Cancer Res Commun. 2025 Sep 1;5(9):1714-1727. doi: 10.1158/2767-9764.CRC-25-0172. PubMed |
| A non-apoptotic caspase-8-meteorin pathway in hepatocytes promotes MASH fibrosis. Wang X, Moore MP, Shi H, Xiao Y, Zhang J, Faccioli LAP, Hu Z, Khalid S, Saleheen D, Stupack DG, Kisseleva T, Soto Gutierrez A, Lazar MA, Tabas I. Nat Metab. 2025 Oct;7(10):2067-2082. doi: 10.1038/s42255-025-01355-1. Epub 2025 Sep 26. PubMed |
| Hepatocyte-specific epidermal growth factor receptor (EGFR) deletion attenuates acetaminophen-induced liver injury in mice. Jain S, Williams G, Mukherjee R, Orr A, Liu JJ, Liu S, Locker J, Bhushan B. Toxicol Sci. 2026 Jan 30;209(1):kfaf151. doi: 10.1093/toxsci/kfaf151. PubMed |
| Diploid hepatocytes resist acetaminophen-induced liver injury through suppressed JNK signaling. Wilson SR, Delgado ER, Alencastro F, Loewenstein RL, Leek MP, Peters LR, Kamel K, Wilkinson PD, Jain S, Locker J, Liu S, Bhushan B, Duncan AW. Cell Death Dis. 2026 Feb 3;17(1):203. doi: 10.1038/s41419-026-08448-z. PubMed |
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