pCAG-NLS(SV40)x2-rAPOBEC1-gs-XTEN-gs-hdLbCas12a(D832A)-gs-UGI-NLS(SV40)(LbBE1.4) (RTW1293) Citations (1)

Originally described in: Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Kleinstiver BP, Sousa AA, Walton RT, Tak YE, Hsu JY, Clement K, Welch MM, Horng JE, Malagon-Lopez J, Scarfo I, Maus MV, Pinello L, Aryee MJ, Joung JK Nat Biotechnol. 2019 Feb 11. pii: 10.1038/s41587-018-0011-0. doi: 10.1038/s41587-018-0011-0. PubMed Journal

Articles Citing pCAG-NLS(SV40)x2-rAPOBEC1-gs-XTEN-gs-hdLbCas12a(D832A)-gs-UGI-NLS(SV40)(LbBE1.4) (RTW1293)

Articles
Directed evolution expands CRISPR-Cas12a genome-editing capacity. Ma E, Chen K, Shi H, Wasko KM, Esain-Garcia I, Trinidad MI, Zhou K, Ye J, Doudna JA. Nucleic Acids Res. 2025 Jul 8;53(13):gkaf649. doi: 10.1093/nar/gkaf649. PubMed Associated Plasmids pEM1_Euk_2NLS-WT ( LbCas12a)-2NLS pEM2_Euk_2NLS-RVQ (LbCas12a)-2NLS pEM3_Euk_2NLS-Flex-Cas12a (LbCas12a)-2NLS pEM4_CL7_Bac_2NLS-WT (LbCas12a)-4NLS pEM5_CL7_Bac_2NLS-Lbm6 (LbCas12a)-4NLS More ...

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