SaKKH-ABEmax Citations (3)
Originally described in: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.Huang TP, Zhao KT, Miller SM, Gaudelli NM, Oakes BL, Fellmann C, Savage DF, Liu DR Nat Biotechnol. 2019 May 20. pii: 10.1038/s41587-019-0134-y. doi: 10.1038/s41587-019-0134-y. PubMed Journal
Articles Citing SaKKH-ABEmax
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Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.
Villiger L, Schmidheini L, Mathis N, Rothgangl T, Marquart K, Schwank G.
Mol Ther Nucleic Acids. 2021 Aug 26;26:502-510. doi: 10.1016/j.omtn.2021.08.025. eCollection 2021 Dec 3.
PubMed
Associated Plasmids |
| One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids. Geurts MH, Gandhi S, Boretto MG, Akkerman N, Derks LLM, van Son G, Celotti M, Harshuk-Shabso S, Peci F, Begthel H, Hendriks D, Schurmann P, Andersson-Rolf A, Chuva de Sousa Lopes SM, van Es JH, van Boxtel R, Clevers H. Nat Commun. 2023 Aug 17;14(1):4998. doi: 10.1038/s41467-023-40701-3. PubMed |
| Systematic empirical evaluation of individual base editing targets: Validating therapeutic targets in USH2A and comparison of methods. Tachida Y, Manian KV, Butcher R, Levy JM, Pendse N, Hennessey E, Liu DR, Pierce EA, Liu Q, Comander J. Mol Ther. 2025 Apr 2;33(4):1466-1484. doi: 10.1016/j.ymthe.2025.01.042. Epub 2025 Jan 28. PubMed |
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