pBLO 62.5 Citations (4)
Originally described in: CasX enzymes comprise a distinct family of RNA-guided genome editors.Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brotzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA Nature. 2019 Feb 4. pii: 10.1038/s41586-019-0908-x. doi: 10.1038/s41586-019-0908-x. PubMed Journal
Articles Citing pBLO 62.5
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Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.
Tsuchida CA, Zhang S, Doost MS, Zhao Y, Wang J, O'Brien E, Fang H, Li CP, Li D, Hai ZY, Chuck J, Brotzmann J, Vartoumian A, Burstein D, Chen XW, Nogales E, Doudna JA, Liu JG.
Mol Cell. 2022 Mar 17;82(6):1199-1209.e6. doi: 10.1016/j.molcel.2022.02.002. Epub 2022 Feb 25.
PubMed
Associated Plasmids |
Quantification of Genome Editing and Transcriptional Control Capabilities Reveals Hierarchies among Diverse CRISPR/Cas Systems in Human Cells.
Escobar M, Li J, Patel A, Liu S, Xu Q, Hilton IB.
ACS Synth Biol. 2022 Oct 21;11(10):3239-3250. doi: 10.1021/acssynbio.2c00156. Epub 2022 Sep 26.
PubMed
Associated Plasmids |
| CAS12e (CASX2) CLEAVAGE OF CCR5: IMPACT OF GUIDE RNA LENGTH AND PAM SEQUENCE ON CLEAVAGE ACTIVITY. Armstrong DA, Hudson TR, Hodge CA, Hampton TH, Howell AL, Hayden MS. bioRxiv. 2023 Jan 2:2023.01.02.522476. doi: 10.1101/2023.01.02.522476. Preprint. PubMed |
| PlmCas12e (CasX2) cleavage of CCR5: impact of guide RNA spacer length and PAM sequence on cleavage activity. Armstrong DA, Hudson TR, Hodge CA, Hampton TH, Howell AL, Hayden MS. RNA Biol. 2023 Jan;20(1):296-305. doi: 10.1080/15476286.2023.2221510. PubMed |
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