Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2 Citations (3)

Originally described in: Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.
Lawson KA, Sousa CM, Zhang X, Kim E, Akthar R, Caumanns JJ, Yao Y, Mikolajewicz N, Ross C, Brown KR, Zid AA, Fan ZP, Hui S, Krall JA, Simons DM, Slater CJ, De Jesus V, Tang L, Singh R, Goldford JE, Martin S, Huang Q, Francis EA, Habsid A, Climie R, Tieu D, Wei J, Li R, Tong AHY, Aregger M, Chan KS, Han H, Wang X, Mero P, Brumell JH, Finelli A, Ailles L, Bader G, Smolen GA, Kingsbury GA, Hart T, Kung C, Moffat J Nature. 2020 Oct;586(7827):120-126. doi: 10.1038/s41586-020-2746-2. Epub 2020 Sep 23. PubMed Journal

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Articles Citing Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

Articles
FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation. Feng Y, Li C, Stewart JA, Barbulescu P, Seija Desivo N, Alvarez-Quilon A, Pezo RC, Perera MLW, Chan K, Tong AHY, Mohamad-Ramshan R, Berru M, Nakib D, Li G, Kardar GA, Carlyle JR, Moffat J, Durocher D, Di Noia JM, Bhagwat AS, Martin A. Nature. 2021 Dec;600(7888):324-328. doi: 10.1038/s41586-021-04144-4. Epub 2021 Nov 24. PubMed
Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity. Granda Farias A, Feng B, Khan S, Ngo W, Wu JLY, Aguilera-Uribe M, Grewal S, Mero P, Singh SK, Kislinger T, Chan WCW, Moffat J. Cell Rep. 2025 Jul 22;44(7):115921. doi: 10.1016/j.celrep.2025.115921. Epub 2025 Jun 27. PubMed
Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors. Yang W, Guo Q, Quan S, Chalmers ZR, Parker JB, Truica M, Dufficy MF, Kerber MM, Vasan K, Gupta DG, Steffeck AWT, Pan H, Siddiqui M, Pham HT, Schiltz GE, Chakravarti D, Chandel NS, Abdulkadir SA. Sci Adv. 2025 Jul 18;11(29):eadw5228. doi: 10.1126/sciadv.adw5228. Epub 2025 Jul 16. PubMed

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