pLKO.1P POLE1_2 Citations (1)

Originally described in: Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase epsilon.
Sviderskiy VO, Blumenberg L, Gorodetsky E, Karakousi TR, Hirsh N, Alvarez SW, Terzi EM, Kaparos E, Whiten GC, Ssebyala S, Tonzi P, Mir H, Neel BG, Huang TT, Adams S, Ruggles KV, Possemato R Mol Cell. 2020 Oct 28. pii: S1097-2765(20)30723-1. doi: 10.1016/j.molcel.2020.10.016. PubMed Journal

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Articles Citing pLKO.1P POLE1_2

Articles
The CIC::DUX4 oncoprotein maintains DNA integrity through direct regulation of the catalytic subunit of DNA polymerase epsilon (POLE). Kosibaty Z, Luck C, Okimoto RA. Oncogene. 2025 Oct;44(38):3598-3608. doi: 10.1038/s41388-025-03507-9. Epub 2025 Aug 4. PubMed

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