Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pSin-EF2-Nanog-Pur Citations (36)

Originally described in: Induced pluripotent stem cell lines derived from human somatic cells.
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S, Nie J, Jonsdottir GA, Ruotti V, Stewart R, Slukvin II, Thomson JA Science. 2007 Dec 21. 318(5858):1917-20.
PubMed Journal

Articles Citing pSin-EF2-Nanog-Pur

Articles
Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer. Meng HM, Zheng P, Wang XY, Liu C, Sui HM, Wu SJ, Zhou J, Ding YQ, Li J. Cancer Biol Ther. 2010 Feb;9(4):295-302. doi: 10.4161/cbt.9.4.10666. Epub 2009 Dec 22. PubMed
Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors. Yakubov E, Rechavi G, Rozenblatt S, Givol D. Biochem Biophys Res Commun. 2010 Mar 26. 394(1):189-93. PubMed
Engineering of human pluripotent stem cells by AAV-mediated gene targeting. Khan IF, Hirata RK, Wang PR, Li Y, Kho J, Nelson A, Huo Y, Zavaljevski M, Ware C, Russell DW. Mol Ther. 2010 Jun;18(6):1192-9. doi: 10.1038/mt.2010.55. Epub 2010 Apr 20. PubMed
Effects of estrogen on the proportion of stem cells in the breast. Simoes BM, Piva M, Iriondo O, Comaills V, Lopez-Ruiz JA, Zabalza I, Mieza JA, Acinas O, Vivanco MD. Breast Cancer Res Treat. 2011 Aug;129(1):23-35. doi: 10.1007/s10549-010-1169-4. Epub 2010 Sep 22. PubMed
Efficient preparation and labeling of human induced pluripotent stem cells by nanotechnology. Ruan J, Shen J, Wang Z, Ji J, Song H, Wang K, Liu B, Li J, Cui D. Int J Nanomedicine. 2011;6:425-35. doi: 10.2147/IJN.S16498. Epub 2011 Feb 21. PubMed
Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection. Dick E, Matsa E, Young LE, Darling D, Denning C. Nat Protoc. 2011 Jun;6(6):701-14. doi: 10.1038/nprot.2011.320. Epub 2011 May 5. PubMed
Normal collagen and bone production by gene-targeted human osteogenesis imperfecta iPSCs. Deyle DR, Khan IF, Ren G, Wang PR, Kho J, Schwarze U, Russell DW. Mol Ther. 2012 Jan;20(1):204-13. doi: 10.1038/mt.2011.209. Epub 2011 Oct 25. PubMed
Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation. Wang X, Wang J, Huang V, Place RF, Li LC. Biochem J. 2012 May 1;443(3):821-8. doi: 10.1042/BJ20111491. PubMed
Cyclohexylmethyl Flavonoids Suppress Propagation of Breast Cancer Stem Cells via Downregulation of NANOG. Liao WY, Liaw CC, Huang YC, Han HY, Hsu HW, Hwang SM, Kuo SC, Shen CN. Evid Based Complement Alternat Med. 2013;2013:170261. doi: 10.1155/2013/170261. Epub 2013 Apr 4. PubMed
CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia. Di Pasquale E, Lodola F, Miragoli M, Denegri M, Avelino-Cruz JE, Buonocore M, Nakahama H, Portararo P, Bloise R, Napolitano C, Condorelli G, Priori SG. Cell Death Dis. 2013 Oct 10;4:e843. doi: 10.1038/cddis.2013.369. PubMed
TET2 deficiency inhibits mesoderm and hematopoietic differentiation in human embryonic stem cells. Langlois T, da Costa Reis Monte-Mor B, Lenglet G, Droin N, Marty C, Le Couedic JP, Almire C, Auger N, Mercher T, Delhommeau F, Christensen J, Helin K, Debili N, Fuks F, Bernard OA, Solary E, Vainchenker W, Plo I. Stem Cells. 2014 Aug;32(8):2084-97. doi: 10.1002/stem.1718. PubMed
Differentiation of primordial germ cells from induced pluripotent stem cells of primary ovarian insufficiency. Leng L, Tan Y, Gong F, Hu L, Ouyang Q, Zhao Y, Lu G, Lin G. Hum Reprod. 2015 Mar;30(3):737-48. doi: 10.1093/humrep/deu358. Epub 2015 Jan 12. PubMed
Cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin. Gurruchaga H, Ciriza J, Saenz Del Burgo L, Rodriguez-Madoz JR, Santos E, Prosper F, Hernandez RM, Orive G, Pedraz JL. Int J Pharm. 2015 May 15;485(1-2):15-24. doi: 10.1016/j.ijpharm.2015.02.047. Epub 2015 Feb 20. PubMed
RELB Alters Proliferation of Human Pluripotent Stem Cells via IMP3- and LIN28-Mediated Modulation of the Expression of IGF2 and Other Cell-Cycle Regulators. Thakar NY, Ovchinnikov DA, Hastie ML, Gorman J, Wolvetang EJ. Stem Cells Dev. 2015 May 5. PubMed
piggyBac insertional mutagenesis screen identifies a role for nuclear RHOA in human ES cell differentiation. Gayle S, Pan Y, Landrette S, Xu T. Stem Cell Reports. 2015 May 12;4(5):926-38. doi: 10.1016/j.stemcr.2015.03.001. Epub 2015 Apr 9. PubMed
The pluripotency factor NANOG promotes the formation of squamous cell carcinomas. Palla AR, Piazzolla D, Alcazar N, Canamero M, Grana O, Gomez-Lopez G, Dominguez O, Duenas M, Paramio JM, Serrano M. Sci Rep. 2015 May 19;5:10205. doi: 10.1038/srep10205. PubMed
Regulation of Nuclear Receptor Nur77 by miR-124. Tenga A, Beard JA, Takwi A, Wang YM, Chen T. PLoS One. 2016 Feb 3;11(2):e0148433. doi: 10.1371/journal.pone.0148433. eCollection 2016. PubMed
PAX7 is a required target for microRNA-206-induced differentiation of fusion-negative rhabdomyosarcoma. Hanna JA, Garcia MR, Go JC, Finkelstein D, Kodali K, Pagala V, Wang X, Peng J, Hatley ME. Cell Death Dis. 2016 Jun 9;7(6):e2256. doi: 10.1038/cddis.2016.159. PubMed
Derivation of Patient Specific Pluripotent Stem Cells Using Clinically Discarded Cumulus Cells. Chang WF, Hwu YM, Xu J, Lin CJ, Wang SW, Cheng AS, Lu J, Lu CH, Sung LY. PLoS One. 2016 Nov 1;11(11):e0165715. doi: 10.1371/journal.pone.0165715. eCollection 2016. PubMed
Generation of induced pluripotent stem cells (iPSCs) from a retinoblastoma patient carrying a c.2663G>A mutation in RB1 gene. Zeng S, Liu L, Ouyang Q, Zhao Y, Lin G, Hu L, Li W. Stem Cell Res. 2016 Sep;17(2):208-211. doi: 10.1016/j.scr.2016.08.015. Epub 2016 Aug 28. PubMed
LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency. Tsanov KM, Pearson DS, Wu Z, Han A, Triboulet R, Seligson MT, Powers JT, Osborne JK, Kane S, Gygi SP, Gregory RI, Daley GQ. Nat Cell Biol. 2017 Jan;19(1):60-67. doi: 10.1038/ncb3453. Epub 2016 Dec 19. PubMed
Thymosin beta 10 is a key regulator of tumorigenesis and metastasis and a novel serum marker in breast cancer. Zhang X, Ren D, Guo L, Wang L, Wu S, Lin C, Ye L, Zhu J, Li J, Song L, Lin H, He Z. Breast Cancer Res. 2017 Feb 8;19(1):15. doi: 10.1186/s13058-016-0785-2. PubMed
HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells. Shah M, Cardenas R, Wang B, Persson J, Mongan NP, Grabowska A, Allegrucci C. Mol Cancer. 2017 Feb 16;16(1):38. doi: 10.1186/s12943-017-0605-z. PubMed
Bovine trophectoderm cells induced from bovine fibroblasts with induced pluripotent stem cell reprogramming factors. Talbot NC, Sparks WO, Phillips CE, Ealy AD, Powell AM, Caperna TJ, Garrett WM, Donovan DM, Blomberg LA. Mol Reprod Dev. 2017 Jun;84(6):468-485. doi: 10.1002/mrd.22797. Epub 2017 Apr 12. PubMed
LSD1 modulates the non-canonical integrin beta3 signaling pathway in non-small cell lung carcinoma cells. Lim SY, Macheleidt I, Dalvi P, Schafer SC, Kerick M, Ozretic L, Ortiz-Cuaran S, George J, Merkelbach-Bruse S, Wolf J, Timmermann B, Thomas RK, Schweiger MR, Buettner R, Odenthal M. Sci Rep. 2017 Aug 31;7(1):10292. doi: 10.1038/s41598-017-09554-x. PubMed
TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway. Wang X, Sun D, Tai J, Chen S, Yu M, Ren D, Wang L. J Exp Clin Cancer Res. 2018 Feb 13;37(1):27. doi: 10.1186/s13046-018-0683-9. PubMed
Columnar Injection for Intracerebral Cell Therapy. Schweitzer JS, Song B, Leblanc PR, Feitosa M, Carter BS, Kim KS. Oper Neurosurg (Hagerstown). 2019 Jun 19. pii: 5520487. doi: 10.1093/ons/opz143. PubMed
Towards a surrogate system to express human lipid binding TCRs. Wang R, Pscheid R, Ghumra A, Kan LYL, Cochrane S, Fairclough L, Alcocer MJC. Biotechnol Lett. 2019 Oct;41(10):1095-1104. doi: 10.1007/s10529-019-02713-2. Epub 2019 Jul 26. PubMed

Associated Plasmids

Effect of heart ischemia and administration route on biodistribution and transduction efficiency of AAV9 vectors. Garcia-Olloqui P, Rodriguez-Madoz JR, Di Scala M, Abizanda G, Vales A, Olague C, Iglesias-Garcia O, Larequi E, Aguado-Alvaro LP, Ruiz-Villalba A, Prosper F, Gonzalez-Aseguinolaza G, Pelacho B. J Tissue Eng Regen Med. 2020 Jan;14(1):123-134. doi: 10.1002/term.2974. Epub 2019 Dec 22. PubMed
Efficient Modulation of TP53 Expression in Human Induced Pluripotent Stem Cells. Uhlmann C, Kuhn LM, Tigges J, Fritsche E, Kahlert UD. Curr Protoc Stem Cell Biol. 2020 Mar;52(1):e102. doi: 10.1002/cpsc.102. PubMed
Genes Involved in the Transcriptional Regulation of Pluripotency Are Expressed in Malignant Tumors of the Uterine Cervix and Can Induce Tumorigenic Capacity in a Nontumorigenic Cell Line. Ruiz G, Valencia-Gonzalez HA, Perez-Montiel D, Munoz F, Ocadiz-Delgado R, Fernandez-Retana J, Perez-Plasencia C, Resendis-Antonio O, Gariglio P, Garcia-Carranca A. Stem Cells Int. 2019 Dec 1;2019:7683817. doi: 10.1155/2019/7683817. eCollection 2019. PubMed
Effects of Survival Motor Neuron Protein on Germ Cell Development in Mouse and Human. Chang WF, Peng M, Hsu J, Xu J, Cho HC, Hsieh-Li HM, Liu JL, Lu CH, Sung LY. Int J Mol Sci. 2021 Jan 11;22(2). pii: ijms22020661. doi: 10.3390/ijms22020661. PubMed
A phenotypically supervised single-cell analysis protocol to study within-cell-type heterogeneity of cultured mammalian cells. Chen K, Ozturk K, Liefeld T, Reich M, Mesirov JP, Carter H, Fraley SI. STAR Protoc. 2021 May 25;2(2):100561. doi: 10.1016/j.xpro.2021.100561. eCollection 2021 Jun 18. PubMed
Nanog, in Cooperation with AP1, Increases the Expression of E6/E7 Oncogenes from HPV Types 16/18. Diaz-Tejeda Y, Guido-Jimenez MC, Lopez-Carbajal H, Amador-Molina A, Mendez-Martinez R, Gariglio-Vidal P, Lizano M, Garcia-Carranca A. Viruses. 2021 Jul 28;13(8). pii: v13081482. doi: 10.3390/v13081482. PubMed
TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway. Oh SJ, Lim JY, Son MK, Ahn JH, Song KH, Lee HJ, Kim S, Cho EH, Chung JY, Cho H, Kim H, Kim JH, Park J, Choi J, Hwang SW, Kim TW. Nat Commun. 2023 May 10;14(1):2691. doi: 10.1038/s41467-023-38318-7. PubMed
ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells. Tsai LK, Peng M, Chang CC, Wen L, Liu L, Liang X, Chen YE, Xu J, Sung LY. Cell Biosci. 2023 Oct 24;13(1):193. doi: 10.1186/s13578-023-01140-1. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.