lentiCRISPR v2 puro - CRBN (#1) Citations (3)

Originally described in: A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer.
Lier S, Sellmer A, Orben F, Heinzlmeir S, Krauss L, Schneeweis C, Hassan Z, Schneider C, Schafer A, Pongratz H, Engleitner T, Ollinger R, Kuisl A, Bassermann F, Schlag C, Kong B, Dove S, Kuster B, Rad R, Reichert M, Wirth M, Saur D, Mahboobi S, Schneider G Bioorg Chem. 2021 Nov 20:105505. doi: 10.1016/j.bioorg.2021.105505. PubMed Journal

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Articles Citing lentiCRISPR v2 puro - CRBN (#1)

Articles
Targeting of IRAK4 and GSPT1 enhances therapeutic efficacy in AML via c-Myc destabilization. Vick EJ, Hassan A, Choi K, Bennett J, Muto T, Clough CA, Culver-Cochran AE, Hueneman K, Bolanos LC, Wunderlich M, Zhang X, McKnight C, Ceribelli M, Holland D, Klumpp-Thomas C, Greis KD, Thomas CJ, Starczynowski DT. Leukemia. 2025 Sep;39(9):2163-2173. doi: 10.1038/s41375-025-02695-3. Epub 2025 Jul 16. PubMed
Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics. Steger M, Nishiguchi G, Wu Q, Schwalb B, Shashikadze B, McGowan K, Actis M, Aggarwal A, Shi Z, Price J, Mayasundari A, Yang L, Bednarz AH, Machata S, Graef T, Bartoschek D, Demichev V, Ohmayer U, Yang J, Daub H, Rankovic Z. Nat Commun. 2025 Aug 20;16(1):7773. doi: 10.1038/s41467-025-62829-0. PubMed
Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia. Uible EE, Choi I, Clough CA, Hassan A, Anandappa AJ, Fisher J, Karki B, Hueneman K, Choi K, Vick EJ, Seibel W, Greis KD, Lee L, Jones C, Chlon TM, Henao-Mejia J, Pasare C, Cunningham JT, Volk AG, Starczynowski DT. Cell Chem Biol. 2026 Jan 15;33(1):59-73.e10. doi: 10.1016/j.chembiol.2025.12.002. Epub 2026 Jan 6. PubMed

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