plRL58 Citations (10)

Originally described in: Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.
Bosch B, DeJesus MA, Poulton NC, Zhang W, Engelhart CA, Zaveri A, Lavalette S, Ruecker N, Trujillo C, Wallach JB, Li S, Ehrt S, Chait BT, Schnappinger D, Rock JM Cell. 2021 Jul 16. pii: S0092-8674(21)00824-2. doi: 10.1016/j.cell.2021.06.033. PubMed Journal

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Articles Citing plRL58

Articles
The essential M. tuberculosis Clp protease is functionally asymmetric in vivo. d'Andrea FB, Poulton NC, Froom R, Tam K, Campbell EA, Rock JM. Sci Adv. 2022 May 6;8(18):eabn7943. doi: 10.1126/sciadv.abn7943. Epub 2022 May 4. PubMed
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis. Li S, Poulton NC, Chang JS, Azadian ZA, DeJesus MA, Ruecker N, Zimmerman MD, Eckartt KA, Bosch B, Engelhart CA, Sullivan DF, Gengenbacher M, Dartois VA, Schnappinger D, Rock JM. Nat Microbiol. 2022 Jun;7(6):766-779. doi: 10.1038/s41564-022-01130-y. Epub 2022 May 30. PubMed
Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis. Wong AI, Beites T, Planck KA, Fieweger RA, Eckartt KA, Li S, Poulton NC, VanderVen BC, Rhee KY, Schnappinger D, Ehrt S, Rock J. Elife. 2023 Feb 22;12:e81177. doi: 10.7554/eLife.81177. PubMed
Incomplete transcripts dominate the Mycobacterium tuberculosis transcriptome. Ju X, Li S, Froom R, Wang L, Lilic M, Delbeau M, Campbell EA, Rock JM, Liu S. Nature. 2024 Mar;627(8003):424-430. doi: 10.1038/s41586-024-07105-9. Epub 2024 Feb 28. PubMed
Compensatory evolution in NusG improves fitness of drug-resistant M. tuberculosis. Eckartt KA, Delbeau M, Munsamy-Govender V, DeJesus MA, Azadian ZA, Reddy AK, Chandanani J, Poulton NC, Quinones-Garcia S, Bosch B, Landick R, Campbell EA, Rock JM. Nature. 2024 Apr;628(8006):186-194. doi: 10.1038/s41586-024-07206-5. Epub 2024 Mar 20. PubMed
Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus. McGowen K, Funck T, Wang X, Zinga S, Wolf ID, Akusobi CC, Denkinger CM, Rubin EJ, Sullivan MR. bioRxiv [Preprint]. 2024 Aug 24:2024.08.23.609441. doi: 10.1101/2024.08.23.609441. PubMed
A trans-Translation Inhibitor is Potentiated by Zinc and Kills Mycobacterium tuberculosis and Nontuberculous Mycobacteria. Varshney A, Jia Z, Howe MD, Keiler KC, Baughn AD. ACS Infect Dis. 2025 May 9;11(5):1140-1152. doi: 10.1021/acsinfecdis.4c00963. Epub 2025 Apr 9. PubMed
Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus. McGowen K, Funck T, Wang X, Zinga S, Wolf ID, Akusobi C, Denkinger CM, Rubin EJ, Sullivan MR. PLoS Pathog. 2025 Apr 10;21(4):e1013027. doi: 10.1371/journal.ppat.1013027. eCollection 2025 Apr. PubMed
Genes required for Mycobacterium tuberculosis to survive the transition from aerosol to pulmonary alveolar lining fluid and early infection in a model of transmission. Singh PR, Mishra S, Jinich A, Jiang X, Tsang F, DeJesus M, Rhee KY, Kaner RJ, Leopold PL, Crystal RG, Nathan C. bioRxiv [Preprint]. 2025 Sep 15:2025.09.15.676370. doi: 10.1101/2025.09.15.676370. PubMed
Mycobacterium Transcriptional Factor BlaI Regulates Cell Division and Growth and Potentiates beta-Lactam Antibiotic Efficacy Against Mycobacteria. Xu J, Zhang M, Xie F, Zhen J, Abuliken Y, Gao C, Dai Y, Jiang Z, Li P, Xie J. Microorganisms. 2025 Sep 25;13(10):2245. doi: 10.3390/microorganisms13102245. PubMed

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