pBABE-neo Citations (35)

Originally described in: Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line.
Morgenstern JP, Land H Nucleic Acids Res. 1990 Jun 25;18(12):3587-96. PubMed

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Articles Citing pBABE-neo

Articles
Novel isolation and biochemical characterization of immortalized fibroblasts for tissue engineering vocal fold lamina propria. Chen X, Thibeault SL. Tissue Eng Part C Methods. 2009 Jun;15(2):201-12. doi: 10.1089/ten.tec.2008.0390. PubMed
Genetic and genomic analyses of RNA polymerase II-pausing factor in regulation of mammalian transcription and cell growth. Sun J, Pan H, Lei C, Yuan B, Nair SJ, April C, Parameswaran B, Klotzle B, Fan JB, Ruan J, Li R. J Biol Chem. 2011 Oct 21;286(42):36248-57. doi: 10.1074/jbc.M111.269167. Epub 2011 Aug 24. PubMed
Creation and validation of a ligation-independent cloning (LIC) retroviral vector for stable gene transduction in mammalian cells. Patel A, Munoz A, Halvorsen K, Rai P. BMC Biotechnol. 2012 Jan 16;12:3. doi: 10.1186/1472-6750-12-3. PubMed Associated Plasmids pBLIC-puro pBLIC-neo
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Perez-Mancera PA, Rust AG, van der Weyden L, Kristiansen G, Li A, Sarver AL, Silverstein KA, Grutzmann R, Aust D, Rummele P, Knosel T, Herd C, Stemple DL, Kettleborough R, Brosnan JA, Li A, Morgan R, Knight S, Yu J, Stegeman S, Collier LS, ten Hoeve JJ, de Ridder J, Klein AP, Goggins M, Hruban RH, Chang DK, Biankin AV, Grimmond SM, Wessels LF, Wood SA, Iacobuzio-Donahue CA, Pilarsky C, Largaespada DA, Adams DJ, Tuveson DA. Nature. 2012 Apr 29;486(7402):266-70. doi: 10.1038/nature11114. PubMed
Transformation of human ovarian surface epithelial cells by Kruppel-like factor 8. Lu H, Wang X, Urvalek AM, Li T, Xie H, Yu L, Zhao J. Oncogene. 2014 Jan 2;33(1):10-8. doi: 10.1038/onc.2012.545. Epub 2012 Dec 10. PubMed
Kruppel-like factor 8 promotes tumorigenic mammary stem cell induction by targeting miR-146a. Wang X, Lu H, Li T, Yu L, Liu G, Peng X, Zhao J. Am J Cancer Res. 2013 Aug 14;3(4):356-73. eCollection 2013. PubMed
Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B. Pan H, Zhao X, Zhang X, Abouelsoud M, Sun J, April C, Amleh A, Fan JB, Hu Y, Li R. PLoS One. 2015 May 26;10(5):e0127422. doi: 10.1371/journal.pone.0127422. eCollection 2015. PubMed
Hedgehog and retinoid signaling alters multiple myeloma microenvironment and generates bortezomib resistance. Alonso S, Hernandez D, Chang YT, Gocke CB, McCray M, Varadhan R, Matsui WH, Jones RJ, Ghiaur G. J Clin Invest. 2016 Dec 1;126(12):4460-4468. doi: 10.1172/JCI88152. Epub 2016 Oct 24. PubMed
Destabilization of the TWIST1/E12 complex dimerization following the R154P point-mutation of TWIST1: an in silico approach. Bouard C, Terreux R, Tissier A, Jacqueroud L, Vigneron A, Ansieau S, Puisieux A, Payen L. BMC Struct Biol. 2017 May 18;17(1):6. doi: 10.1186/s12900-017-0076-x. PubMed
Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors. Mahfouz N, Tahtouh R, Alaaeddine N, El Hajj J, Sarkis R, Hachem R, Raad I, Hilal G. PLoS One. 2017 Jun 8;12(6):e0179202. doi: 10.1371/journal.pone.0179202. eCollection 2017. PubMed
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle NK, Dhar D, Banerjee S, Fagman JB, Browne CD, Umemura A, Valasek MA, Kessler H, Tarin D, Goggins M, Reya T, Diaz-Meco M, Moscat J, Karin M. Cancer Cell. 2017 Dec 11;32(6):824-839.e8. doi: 10.1016/j.ccell.2017.10.011. Epub 2017 Nov 16. PubMed
A small molecule screen to identify regulators of let-7 targets. Cinkornpumin J, Roos M, Nguyen L, Liu X, Gaeta X, Lin S, Chan DN, Liu A, Gregory RI, Jung M, Chute J, Zhu H, Lowry WE. Sci Rep. 2017 Nov 21;7(1):15973. doi: 10.1038/s41598-017-16258-9. PubMed
Metabolic regulation of transcription through compartmentalized NAD(+) biosynthesis. Ryu KW, Nandu T, Kim J, Challa S, DeBerardinis RJ, Kraus WL. Science. 2018 May 11;360(6389). pii: 360/6389/eaan5780. doi: 10.1126/science.aan5780. PubMed
IKappaKappaepsilon cooperates with either MEK or non-canonical NF-kB driving growth of triple-negative breast cancer cells in different contexts. House CD, Grajales V, Ozaki M, Jordan E, Wubneh H, Kimble DC, James JM, Kim MK, Annunziata CM. BMC Cancer. 2018 May 25;18(1):595. doi: 10.1186/s12885-018-4507-2. PubMed
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis. Liu S, Hausmann S, Carlson SM, Fuentes ME, Francis JW, Pillai R, Lofgren SM, Hulea L, Tandoc K, Lu J, Li A, Nguyen ND, Caporicci M, Kim MP, Maitra A, Wang H, Wistuba II, Porco JA Jr, Bassik MC, Elias JE, Song J, Topisirovic I, Van Rechem C, Mazur PK, Gozani O. Cell. 2019 Jan 24;176(3):491-504.e21. doi: 10.1016/j.cell.2018.11.038. Epub 2019 Jan 3. PubMed
C-terminal BRE inhibits cellular proliferation and increases sensitivity to chemotherapeutic drugs of MLL-AF9 acute myeloid leukemia cells. Pun CC, Lee KK, Chui YL. Leuk Lymphoma. 2019 May 21:1-9. doi: 10.1080/10428194.2019.1616184. PubMed
PI3Kalpha inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment. Shi JJ, Xing H, Wang YX, Zhang X, Zhan QM, Geng MY, Ding J, Meng LH. Cancer Lett. 2019 Sep 10;459:145-155. doi: 10.1016/j.canlet.2019.05.040. Epub 2019 Jun 4. PubMed
MTHFD2 links RNA methylation to metabolic reprogramming in renal cell carcinoma. Green NH, Galvan DL, Badal SS, Chang BH, LeBleu VS, Long J, Jonasch E, Danesh FR. Oncogene. 2019 Aug;38(34):6211-6225. doi: 10.1038/s41388-019-0869-4. Epub 2019 Jul 9. PubMed
Glucose restriction combined with chemotherapy decreases telomere length and cancer antigen-125 secretion in ovarian carcinoma. Antoun S, Atallah D, Tahtouh R, Assaf MD, Moubarak M, Ayoub EN, Chahine G, Hilal G. Oncol Lett. 2020 Feb;19(2):1338-1350. doi: 10.3892/ol.2019.11233. Epub 2019 Dec 20. PubMed
SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy. Wang Z, Hausmann S, Lyu R, Li TM, Lofgren SM, Flores NM, Fuentes ME, Caporicci M, Yang Z, Meiners MJ, Cheek MA, Howard SA, Zhang L, Elias JE, Kim MP, Maitra A, Wang H, Bassik MC, Keogh MC, Sage J, Gozani O, Mazur PK. Cancer Cell. 2020 Jun 8;37(6):834-849.e13. doi: 10.1016/j.ccell.2020.04.014. Epub 2020 May 21. PubMed
Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining. Francica P, Mutlu M, Blomen VA, Oliveira C, Nowicka Z, Trenner A, Gerhards NM, Bouwman P, Stickel E, Hekkelman ML, Lingg L, Klebic I, van de Ven M, de Korte-Grimmerink R, Howald D, Jonkers J, Sartori AA, Fendler W, Chapman JR, Brummelkamp T, Rottenberg S. Cell Rep. 2020 Aug 25;32(8):108068. doi: 10.1016/j.celrep.2020.108068. PubMed
Laser Micro-Irradiation to Study DNA Recruitment During S Phase. Miwatani-Minter B, Rona G. J Vis Exp. 2021 Apr 16;(170). doi: 10.3791/62466. PubMed
METTL1-mediated m(7)G modification of Arg-TCT tRNA drives oncogenic transformation. Orellana EA, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, Lim J, Aspris D, Sendinc E, Garyfallos DA, Gu M, Ali R, Gutierrez A, Mikutis S, Bernardes GJL, Fischer ES, Bradley A, Vassiliou GS, Slack FJ, Tzelepis K, Gregory RI. Mol Cell. 2021 Aug 19;81(16):3323-3338.e14. doi: 10.1016/j.molcel.2021.06.031. Epub 2021 Aug 4. PubMed
NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis. Sengupta D, Zeng L, Li Y, Hausmann S, Ghosh D, Yuan G, Nguyen TN, Lyu R, Caporicci M, Morales Benitez A, Coles GL, Kharchenko V, Czaban I, Azhibek D, Fischle W, Jaremko M, Wistuba II, Sage J, Jaremko L, Li W, Mazur PK, Gozani O. Mol Cell. 2021 Nov 4;81(21):4481-4492.e9. doi: 10.1016/j.molcel.2021.08.034. Epub 2021 Sep 22. PubMed
Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer. Ruiz-Fernandez de Cordoba B, Moreno H, Valencia K, Perurena N, Ruedas P, Walle T, Pezonaga-Torres A, Hinojosa J, Guruceaga E, Pineda-Lucena A, Abengozar-Muela M, Cochonneau D, Zandueta C, Martinez-Canarias S, Teijeira A, Ajona D, Ortiz-Espinosa S, Morales X, Ortiz de Solorzano C, Santisteban M, Ramos-Garcia LI, Guembe L, Strnad V, Heymann D, Hervas-Stubbs S, Pio R, Rodriguez-Ruiz ME, de Andrea CE, Vicent S, Melero I, Lecanda F, Martinez-Monge R. Cancer Discov. 2022 May 2;12(5):1356-1377. doi: 10.1158/2159-8290.CD-21-0932. PubMed
Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis. He D, Feng H, Sundberg B, Yang J, Powers J, Christian AH, Wilkinson JE, Monnin C, Avizonis D, Thomas CJ, Friedman RA, Kluger MD, Hollingsworth MA, Grandgenett PM, Klute KA, Toste FD, Chang CJ, Chio IIC. Mol Cell. 2022 Aug 18;82(16):3045-3060.e11. doi: 10.1016/j.molcel.2022.06.005. Epub 2022 Jun 24. PubMed
TGFBR3 supports anoikis through suppressing ATF4 signaling. Hsu YJ, Yin YJ, Tsai KF, Jian CC, Liang ZW, Hsu CY, Wang CC. J Cell Sci. 2022 Sep 1;135(17):jcs258396. doi: 10.1242/jcs.258396. Epub 2022 Aug 30. PubMed
DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer. Miller AL, Perurena N, Gardner A, Hinoue T, Loi P, Laird PW, Cichowski K. Cancer Res. 2023 Jun 2;83(11):1800-1814. doi: 10.1158/0008-5472.CAN-22-0370. PubMed
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability. Ravn-Boess N, Roy N, Hattori T, Bready D, Donaldson H, Lawson C, Lapierre C, Korman A, Rodrick T, Liu E, Frenster JD, Stephan G, Wilcox J, Corrado AD, Cai J, Ronnen R, Wang S, Haddock S, Sabio Ortiz J, Mishkit O, Khodadadi-Jamayran A, Tsirigos A, Fenyo D, Zagzag D, Drube J, Hoffmann C, Perna F, Jones DR, Possemato R, Koide A, Koide S, Park CY, Placantonakis DG. Cell Rep. 2023 Nov 28;42(11):113374. doi: 10.1016/j.celrep.2023.113374. Epub 2023 Nov 8. PubMed
Evidence of steady-state fibroblast subtypes in the normal human breast as cells-of-origin for perturbed-state fibroblasts in breast cancer. Bagger MM, Sjolund J, Kim J, Kohler KT, Villadsen R, Jafari A, Kassem M, Pietras K, Ronnov-Jessen L, Petersen OW. Breast Cancer Res. 2024 Jan 16;26(1):11. doi: 10.1186/s13058-024-01763-3. PubMed
All-trans-retinoic acid modulates glycolysis via H19 and telomerase: the role of mir-let-7a in estrogen receptor-positive breast cancer cells. El Habre R, Aoun R, Tahtouh R, Hilal G. BMC Cancer. 2024 May 21;24(1):615. doi: 10.1186/s12885-024-12379-3. PubMed
Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity. Laquatra C, Magro A, Guarra F, Lambrughi M, Ferrone L, Fracasso G, Bacchin M, La Spina M, Moroni E, Papaleo E, Colombo G, Rasola A. Cell Death Dis. 2025 Mar 12;16(1):172. doi: 10.1038/s41419-025-07467-6. PubMed
Dual ENPP1/ATM depletion blunts DNA damage repair boosting radioimmune efficacy to abrogate triple-negative breast cancer. Ruiz-Fernandez de Cordoba B, Valencia K, Welch C, Moreno H, Martinez-Canarias S, Zandueta C, Gomez E, Calvo A, Otegui N, Echepare M, Garzon I, Ajona D, Lara-Astiaso D, Guruceaga E, Guembe L, Pio R, Melero I, Vicent S, Pastor F, Martinez-Monge R, Lecanda F. Signal Transduct Target Ther. 2025 Jun 13;10(1):185. doi: 10.1038/s41392-025-02271-2. PubMed
An Iron-regulated Signalling Pathway Controls Adipose Browning and Cancer Cachexia. Nam JS, Dixon MS, Ahmadi P, Schilling K, Pan S, Chen Y, Yoon NA, Sun Y, Lu J, Ichimiya S, Genkinger JM, Caffrey TC, Klute KA, Swanson BJ, Grandgenett P, Hollingsworth MA, Sugahara K, Kluger MD, Ferrante A, Diano S, Chio IIC. bioRxiv [Preprint]. 2025 Jul 18:2025.07.16.664180. doi: 10.1101/2025.07.16.664180. PubMed
Improved Methods for the Stable Generation of Human Papillomavirus-Driven Head and Neck Cancer Cell Lines. Le PN, Keysar SB, Miller B, Morton JJ, Chimed TS, Alzofon N, Nieto C, Davies KD, Thomas CM, Weaver AN, Jimeno A. Mol Carcinog. 2025 Nov;64(11):1813-1822. doi: 10.1002/mc.70025. Epub 2025 Aug 12. PubMed

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