pT3EF1aH-myr-Akt Citations (4)
Originally described in: AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathways.Ho C, Wang C, Mattu S, Destefanis G, Ladu S, Delogu S, Armbruster J, Fan L, Lee SA, Jiang L, Dombrowski F, Evert M, Chen X, Calvisi DF Hepatology. 2012 Mar;55(3):833-45. doi: 10.1002/hep.24736. Epub 2011 Dec 19. PubMed Journal
Articles Citing pT3EF1aH-myr-Akt
| Articles |
|---|
| Targeting polycomb repressor complex 2-mediated bivalent promoter epigenetic silencing of secreted frizzled-related protein 1 inhibits cholangiocarcinoma progression. Wu G, Wang Q, Wang D, Xiong F, Liu W, Chen J, Wang B, Huang W, Wang X, Chen Y. Clin Transl Med. 2023 Dec;13(12):e1502. doi: 10.1002/ctm2.1502. PubMed |
| STUB1-mediated K63-linked ubiquitination of UHRF1 promotes the progression of cholangiocarcinoma by maintaining DNA hypermethylation of PLA2G2A. Chen J, Wang D, Wu G, Xiong F, Liu W, Wang Q, Kuai Y, Huang W, Qi Y, Wang B, Chen Y. J Exp Clin Cancer Res. 2024 Sep 13;43(1):260. doi: 10.1186/s13046-024-03186-6. PubMed |
| PPM1G Inhibits Epithelial-Mesenchymal Transition in Cholangiocarcinoma by Catalyzing TET1 Dephosphorylation for Destabilization to Impair Its Targeted Demethylation of the CLDN3 Promoter. Liu W, Kuai Y, Wang D, Chen J, Xiong F, Wu G, Wang Q, Huang W, Qi Y, Wang B, Chen Y. Adv Sci (Weinh). 2024 Dec;11(47):e2407323. doi: 10.1002/advs.202407323. Epub 2024 Oct 30. PubMed |
| Liver-specific gene PGRMC1 blocks c-Myc-induced hepatocarcinogenesis through ER stress-independent PERK activation. Ji F, Zhang J, Mao L, Tan Y, Ye M, He X, Zhao Y, Liu J, Zhang Y, Zhang N, Shi J, Yan J, Cai X, Zhao B, Jin J, Xu P, Roessler S, Zheng X, Ji J. Nat Commun. 2025 Jan 2;16(1):50. doi: 10.1038/s41467-024-55745-2. PubMed |
If you have published an article using this material, please email us at [email protected] to have your article added to this page.