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cytoplasmic EKAR (EGFP-mRFP) Citations (9)

Originally described in: A genetically encoded fluorescent sensor of ERK activity
Harvey CD, Ehrhardt AG, Cellurale C, Zhong H, Yasuda R, Davis RJ, Svoboda K. PNAS 2008 Dec 9;105(49):19264-9
PubMed Journal

Articles Citing cytoplasmic EKAR (EGFP-mRFP)

Endothelin-converting enzyme 1 and beta-arrestins exert spatiotemporal control of substance P-induced inflammatory signals. Jensen DD, Halls ML, Murphy JE, Canals M, Cattaruzza F, Poole DP, Lieu T, Koon HW, Pothoulakis C, Bunnett NW. J Biol Chem. 2014 Jul 18;289(29):20283-94. doi: 10.1074/jbc.M114.578179. Epub 2014 Jun 4. PubMed
Plasma membrane localization of the mu-opioid receptor controls spatiotemporal signaling. Halls ML, Yeatman HR, Nowell CJ, Thompson GL, Gondin AB, Civciristov S, Bunnett NW, Lambert NA, Poole DP, Canals M. Sci Signal. 2016 Feb 9;9(414):ra16. doi: 10.1126/scisignal.aac9177. PubMed
Imaging ERK and PKA Activation in Single Dendritic Spines during Structural Plasticity. Tang S, Yasuda R. Neuron. 2017 Mar 22;93(6):1315-1324.e3. doi: 10.1016/j.neuron.2017.02.032. Epub 2017 Mar 9. PubMed

Associated Plasmids

Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations. Civciristov S, Ellisdon AM, Suderman R, Pon CK, Evans BA, Kleifeld O, Charlton SJ, Hlavacek WS, Canals M, Halls ML. Sci Signal. 2018 Oct 9;11(551). pii: 11/551/eaan1188. doi: 10.1126/scisignal.aan1188. PubMed
Ligand-dependent spatiotemporal signaling profiles of the mu-opioid receptor are controlled by distinct protein-interaction networks. Civciristov S, Huang C, Liu B, Marquez EA, Gondin AB, Schittenhelm RB, Ellisdon AM, Canals M, Halls ML. J Biol Chem. 2019 Nov 1;294(44):16198-16213. doi: 10.1074/jbc.RA119.008685. Epub 2019 Sep 12. PubMed
SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Andres-Alonso M, Ammar MR, Butnaru I, Gomes GM, Acuna Sanhueza G, Raman R, Yuanxiang P, Borgmeyer M, Lopez-Rojas J, Raza SA, Brice N, Hausrat TJ, Macharadze T, Diaz-Gonzalez S, Carlton M, Failla AV, Stork O, Schweizer M, Gundelfinger ED, Kneussel M, Spilker C, Karpova A, Kreutz MR. Nat Commun. 2019 Nov 29;10(1):5448. doi: 10.1038/s41467-019-13224-z. PubMed
Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice. Bang S, Donnelly CR, Luo X, Toro-Moreno M, Tao X, Wang Z, Chandra S, Bortsov AV, Derbyshire ER, Ji RR. Nat Commun. 2021 Mar 17;12(1):1704. doi: 10.1038/s41467-021-21940-8. PubMed
Inhibition of the Proliferation of Human Lung Fibroblasts by Prostacyclin Receptor Agonists is Linked to a Sustained cAMP Signal in the Nucleus. Roberts MJ, May LT, Keen AC, Liu B, Lam T, Charlton SJ, Rosethorne EM, Halls ML. Front Pharmacol. 2021 Apr 29;12:669227. doi: 10.3389/fphar.2021.669227. eCollection 2021. PubMed
Increased intracellular diffusivity of macromolecules within a mammalian cell by low-intensity pulsed ultrasound. Kim H, Choi Y, Kim SY, Pahk KJ. Ultrason Sonochem. 2023 Nov;100:106644. doi: 10.1016/j.ultsonch.2023.106644. Epub 2023 Oct 10. PubMed

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