Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pCDNA3 Flag MKK7B2Jnk1a1 Citations (27)

Originally described in: The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase.
Lei K, Nimnual A, Zong WX, Kennedy NJ, Flavell RA, Thompson CB, Bar-Sagi D, Davis RJ Mol Cell Biol. 2002 Jul . 22(13):4929-42.
PubMed Journal

Articles Citing pCDNA3 Flag MKK7B2Jnk1a1

Articles
Complex inhibitory effects of nitric oxide on autophagy. Sarkar S, Korolchuk VI, Renna M, Imarisio S, Fleming A, Williams A, Garcia-Arencibia M, Rose C, Luo S, Underwood BR, Kroemer G, O'Kane CJ, Rubinsztein DC. Mol Cell. 2011 Jul 8;43(1):19-32. doi: 10.1016/j.molcel.2011.04.029. PubMed
Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite. Cotsiki M, Oehrl W, Samiotaki M, Theodosiou A, Panayotou G. Cell Signal. 2012 Mar;24(3):664-76. doi: 10.1016/j.cellsig.2011.10.015. Epub 2011 Nov 9. PubMed
Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. de Anda FC, Rosario AL, Durak O, Tran T, Graff J, Meletis K, Rei D, Soda T, Madabhushi R, Ginty DD, Kolodkin AL, Tsai LH. Nat Neurosci. 2012 Jun 10;15(7):1022-31. doi: 10.1038/nn.3141. PubMed
Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun N-terminal kinase promotes stress-dependent P-body assembly. Cargnello M, Tcherkezian J, Dorn JF, Huttlin EL, Maddox PS, Gygi SP, Roux PP. Mol Cell Biol. 2012 Nov;32(22):4572-84. doi: 10.1128/MCB.00544-12. Epub 2012 Sep 10. PubMed
Differential regulation of M3/6 (DUSP8) signaling complexes in response to arsenite-induced oxidative stress. Oehrl W, Cotsiki M, Panayotou G. Cell Signal. 2013 Feb;25(2):429-38. doi: 10.1016/j.cellsig.2012.11.010. Epub 2012 Nov 15. PubMed
Myc inhibition impairs autophagosome formation. Toh PP, Luo S, Menzies FM, Rasko T, Wanker EE, Rubinsztein DC. Hum Mol Genet. 2013 Dec 20;22(25):5237-48. doi: 10.1093/hmg/ddt381. Epub 2013 Aug 9. PubMed
The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells. Rui YN, Xu Z, Chen Z, Zhang S. Autophagy. 2015;11(5):812-32. doi: 10.1080/15548627.2015.1034402. PubMed
Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation. Martinez NM, Agosto L, Qiu J, Mallory MJ, Gazzara MR, Barash Y, Fu XD, Lynch KW. Genes Dev. 2015 Oct 1;29(19):2054-66. doi: 10.1101/gad.267245.115. PubMed
TAK1 modulates satellite stem cell homeostasis and skeletal muscle repair. Ogura Y, Hindi SM, Sato S, Xiong G, Akira S, Kumar A. Nat Commun. 2015 Dec 9;6:10123. doi: 10.1038/ncomms10123. PubMed
HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Su KH, Cao J, Tang Z, Dai S, He Y, Sampson SB, Benjamin IJ, Dai C. Nat Cell Biol. 2016 May;18(5):527-39. doi: 10.1038/ncb3335. Epub 2016 Apr 4. PubMed
The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy. Lukey MJ, Greene KS, Erickson JW, Wilson KF, Cerione RA. Nat Commun. 2016 Apr 18;7:11321. doi: 10.1038/ncomms11321. PubMed
Hepatitis C virus promotes virion secretion through cleavage of the Rab7 adaptor protein RILP. Wozniak AL, Long A, Jones-Jamtgaard KN, Weinman SA. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12484-12489. Epub 2016 Oct 17. PubMed

Associated Plasmids

Fibroblast Growth Requires CT10 Regulator of Kinase (Crk) and Crk-like (CrkL). Park T, Koptyra M, Curran T. J Biol Chem. 2016 Dec 16;291(51):26273-26290. Epub 2016 Nov 2. PubMed
Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation. Houssin NS, Bharathan NK, Turner SD, Dickinson AJ. Dev Dyn. 2016 Nov 5. doi: 10.1002/dvdy.24470. PubMed
ABT-737 Synergizes with Cisplatin Bypassing Aberration of Apoptotic Pathway in Non-small Cell Lung Cancer. Kim EY, Jung JY, Kim A, Chang YS, Kim SK. Neoplasia. 2017 Apr;19(4):354-363. doi: 10.1016/j.neo.2017.02.008. Epub 2017 Mar 17. PubMed
JNK-associated scattered growth of YD-10B oral squamous carcinoma cells while maintaining the epithelial phenotype. Lee G, Kim HM. Biochem Biophys Res Commun. 2017 Jun 10;487(4):862-867. doi: 10.1016/j.bbrc.2017.04.142. Epub 2017 Apr 27. PubMed
JNK regulates muscle remodeling via myostatin/SMAD inhibition. Lessard SJ, MacDonald TL, Pathak P, Han MS, Coffey VG, Edge J, Rivas DA, Hirshman MF, Davis RJ, Goodyear LJ. Nat Commun. 2018 Aug 2;9(1):3030. doi: 10.1038/s41467-018-05439-3. PubMed
AIF promotes a JNK1-mediated cadherin switch independently of respiratory chain stabilization. Scott AJ, Walker SA, Krank JJ, Wilkinson AS, Johnson KM, Lewis EM, Wilkinson JC. J Biol Chem. 2018 Sep 21;293(38):14707-14722. doi: 10.1074/jbc.RA118.004022. Epub 2018 Aug 9. PubMed
Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis. Insua-Rodriguez J, Pein M, Hongu T, Meier J, Descot A, Lowy CM, De Braekeleer E, Sinn HP, Spaich S, Sutterlin M, Schneeweiss A, Oskarsson T. EMBO Mol Med. 2018 Oct;10(10). pii: emmm.201809003. doi: 10.15252/emmm.201809003. PubMed
c-Jun N-terminal kinase (JNK)-mediated induction of mSin1 expression and mTORC2 activation in mesenchymal cells during fibrosis. Walker NM, Mazzoni SM, Vittal R, Fingar DC, Lama VN. J Biol Chem. 2018 Nov 2;293(44):17229-17239. doi: 10.1074/jbc.RA118.003926. Epub 2018 Sep 14. PubMed
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs. Pein M, Insua-Rodriguez J, Hongu T, Riedel A, Meier J, Wiedmann L, Decker K, Essers MAG, Sinn HP, Spaich S, Sutterlin M, Schneeweiss A, Trumpp A, Oskarsson T. Nat Commun. 2020 Mar 20;11(1):1494. doi: 10.1038/s41467-020-15188-x. PubMed
JNK suppresses melanogenesis by interfering with CREB-regulated transcription coactivator 3-dependent MITF expression. Kim JH, Hong AR, Kim YH, Yoo H, Kang SW, Chang SE, Song Y. Theranostics. 2020 Mar 4;10(9):4017-4029. doi: 10.7150/thno.41502. eCollection 2020. PubMed
JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction. Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, Antonucci Y, Di Daniele A, Caicci F, Caruana I, Soriano ME, Pigazzi M, Locatelli F, Cecconi F, Campello S. Cell Death Differ. 2020 Apr 28. pii: 10.1038/s41418-020-0540-1. doi: 10.1038/s41418-020-0540-1. PubMed
Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation. Chen CA, Strouz K, Huang KL, Shyu AB. RNA. 2020 Sep;26(9):1143-1159. doi: 10.1261/rna.073528.119. Epub 2020 May 13. PubMed
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation. Yang J, Wang J, Liu Y, Zhang Y, Huang W, Zou Y, Qiu Y, Cai W, Gao J, Zhou H, Wu Y, Liu W, Ding Q, Zhang Y, Yin PH, Tan W. Cell Death Dis. 2021 Jul 15;12(7):707. doi: 10.1038/s41419-021-03995-z. PubMed
Regulation of the Golgi Apparatus by p38 and JNK Kinases during Cellular Stress Responses. Nordgaard C, Tollenaere MAX, Val AMD, Bekker-Jensen DB, Blasius M, Olsen JV, Bekker-Jensen S. Int J Mol Sci. 2021 Sep 4;22(17). pii: ijms22179595. doi: 10.3390/ijms22179595. PubMed
JNK1-Dependent Phosphorylation of GAP-43 Serine 142 is a Novel Molecular Marker for Axonal Growth. Okada M, Kawagoe Y, Takasugi T, Nozumi M, Ito Y, Fukusumi H, Kanemura Y, Fujii Y, Igarashi M. Neurochem Res. 2022 Sep;47(9):2668-2682. doi: 10.1007/s11064-022-03580-6. Epub 2022 Mar 26. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.