pcDNA3-HA2-Keap1 Citations (9)

Originally described in: BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
Furukawa M, Xiong Y Mol Cell Biol. 2005 Jan . 25(1):162-71. PubMed Journal

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Articles Citing pcDNA3-HA2-Keap1

Articles
RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1. Bakkar N, Kousari A, Kovalik T, Li Y, Bowser R. Mol Cell Biol. 2015 Jul 15;35(14):2385-99. doi: 10.1128/MCB.00087-15. Epub 2015 May 4. PubMed
Kelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 Complex. Gong W, Gohla RM, Bowlin KM, Koyano-Nakagawa N, Garry DJ, Shi X. J Biol Chem. 2015 Jun 12;290(24):15350-61. doi: 10.1074/jbc.M114.629956. Epub 2015 May 4. PubMed
Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses. Perez-Leal O, Barrero CA, Merali S. J Biol Chem. 2017 Jul 6. pii: jbc.M116.770925. doi: 10.1074/jbc.M116.770925. PubMed
A catalogue of somatic NRF2 gain-of-function mutations in cancer. Kerins MJ, Ooi A. Sci Rep. 2018 Aug 27;8(1):12846. doi: 10.1038/s41598-018-31281-0. PubMed
IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3beta-Nrf2-BNIP3 Pathway. Riis S, Murray JB, O'Connor R. Cells. 2020 Jan 8;9(1). pii: cells9010147. doi: 10.3390/cells9010147. PubMed
The acetyltransferase p300 regulates NRF2 stability and localization. Ganner A, Pfeiffer ZC, Wingendorf L, Kreis S, Klein M, Walz G, Neumann-Haefelin E. Biochem Biophys Res Commun. 2020 Apr 16;524(4):895-902. doi: 10.1016/j.bbrc.2020.02.006. Epub 2020 Feb 10. PubMed
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds. Castiglione GM, Xu Z, Zhou L, Duh EJ. Nat Commun. 2020 May 18;11(1):2476. doi: 10.1038/s41467-020-16129-4. PubMed
A novel role of KEAP1/PGAM5 complex: ROS sensor for inducing mitophagy. Zeb A, Choubey V, Gupta R, Kuum M, Safiulina D, Vaarmann A, Gogichaishvili N, Liiv M, Ilves I, Tamm K, Veksler V, Kaasik A. Redox Biol. 2021 Dec;48:102186. doi: 10.1016/j.redox.2021.102186. Epub 2021 Nov 11. PubMed
Running a genetic stop sign accelerates oxygen metabolism and energy production in horses. Castiglione GM, Chen X, Xu Z, Dbouk NH, Bose AA, Carmona-Berrio D, Chi EE, Zhou L, Boronina TN, Cole RN, Wu S, Liu AD, Liu TD, Lu H, Kalbfleisch T, Rinker D, Rokas A, Ortved K, Duh EJ. Science. 2025 Mar 28;387(6741):eadr8589. doi: 10.1126/science.adr8589. Epub 2025 Mar 28. PubMed

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