6-ISG-IFN
(Plasmid #231488)

• Purpose: Standard for type I interferon signature (6 genes)
• Depositing Lab: Stefano Volpi
• Publication: Tesser et al Clin Exp Immunol. 2025 Mar 24:uxaf018. doi: 10.1093/cei/uxaf018.

Backbone

• Vector backbone: pCR2.1
• Backbone manufacturer: Invitrogen
• Backbone size w/o insert (bp): 3929
• Total vector size (bp): 5821
• Vector type: qPCR plasmid standard

Growth in Bacteria

• Bacterial Resistance(s): Ampicillin, 100 μg/mL
• Growth Temperature: 37°C
• Growth Strain(s): DH5alpha
• Copy number: High Copy

Gene/Insert 1

• Gene/Insert name: TBP
• Species: H. sapiens (human)
• Insert Size (bp): 203
• Mutation: partial sequence
• Entrez Gene: TBP (a.k.a. GTF2D, GTF2D1, HDL4, SCA17, TBP1, TFIID)

Gene/Insert 2

• Gene/Insert name: IFI27
• Species: H. sapiens (human)
• Insert Size (bp): 199
• Mutation: partial sequence
• Entrez Gene: IFI27 (a.k.a. FAM14D, ISG12, ISG12A, P27)

Gene/Insert 3

• Gene/Insert name: IFI44L
• Species: H. sapiens (human)
• Insert Size (bp): 204
• Mutation: partial sequence
• Entrez Gene: IFI44L (a.k.a. C1orf29, GS3686, TLDC5B)

Gene/Insert 4

• Gene/Insert name: IFIT1
• Species: H. sapiens (human)
• Insert Size (bp): 178
• Mutation: partial sequence
• Entrez Gene: IFIT1 (a.k.a. C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561)

Gene/Insert 5

• Gene/Insert name: ISG15
• Species: H. sapiens (human)
• Insert Size (bp): 191
• Mutation: partial sequence
• Entrez Gene: ISG15 (a.k.a. G1P2, IFI15, IMD38, IP17, UCRP, hUCRP)

Gene/Insert 6

• Gene/Insert name: RSAD2
• Species: H. sapiens (human)
• Insert Size (bp): 252
• Mutation: partial sequence
• Entrez Gene: RSAD2 (a.k.a. SAND, cig33, cig5, vig1)

Gene/Insert 7

• Gene/Insert name: SIGLEC1
• Species: H. sapiens (human)
• Insert Size (bp): 198
• Mutation: partial sequence
• Entrez Gene: SIGLEC1 (a.k.a. CD169, SIGLEC-1, SN)

Gene/Insert 8

• Gene/Insert name: HPRT1
• Species: H. sapiens (human)
• Insert Size (bp): 210
• Mutation: partial sequence
• Entrez Gene: HPRT1 (a.k.a. HGPRT, HPRT)

Gene/Insert 9

• Gene/Insert name: 18s
• Species: H. sapiens (human)
• Insert Size (bp): 140
• Mutation: partial sequence
• Entrez Gene: RPS18 (a.k.a. D6S218E, HKE3, KE-3, KE3, S18, uS13)

Gene/Insert 10

• Gene/Insert name: G6PD
• Species: H. sapiens (human)
• Insert Size (bp): 76
• Mutation: partial sequence
• Entrez Gene: G6PD (a.k.a. CNSHA1, G6PD1)

Resource Information

• Supplemental Documents:
  • 6-ISG-IFN

Terms and Licenses

• Academic/Nonprofit Terms:
  • UBMTA
• Industry Terms:
  • Not Available to Industry