DYRK1A Citations (5)

Originally described in: SGC+year
unpublished

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Articles Citing DYRK1A

Articles
Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase. Zheng Y, Ramsamooj S, Li Q, Johnson JL, Yaron TM, Sharra K, Cantley LC. Sci Rep. 2019 Mar 12;9(1):4190. doi: 10.1038/s41598-019-40950-7. PubMed
Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human beta-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor. Kumar K, Wang P, Wilson J, Zlatanic V, Berrouet C, Khamrui S, Secor C, Swartz EA, Lazarus M, Sanchez R, Stewart AF, Garcia-Ocana A, DeVita RJ. J Med Chem. 2020 Mar 26;63(6):2986-3003. doi: 10.1021/acs.jmedchem.9b01379. Epub 2020 Feb 19. PubMed
1,6-Hexanediol, commonly used to dissolve liquid-liquid phase separated condensates, directly impairs kinase and phosphatase activities. Duster R, Kaltheuner IH, Schmitz M, Geyer M. J Biol Chem. 2021 Jan-Jun;296:100260. doi: 10.1016/j.jbc.2021.100260. Epub 2021 Jan 8. PubMed
Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation. Kaltheuner IH, Anand K, Moecking J, Duster R, Wang J, Gray NS, Geyer M. Nat Commun. 2021 Nov 16;12(1):6607. doi: 10.1038/s41467-021-26935-z. PubMed
Functional characterization of the human Cdk10/Cyclin Q complex. Duster R, Ji Y, Pan KT, Urlaub H, Geyer M. Open Biol. 2022 Mar;12(3):210381. doi: 10.1098/rsob.210381. Epub 2022 Mar 16. PubMed

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